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| Status |
Public on Nov 30, 2016 |
| Title |
Gene array analysis of anaplastic thyroid carcinoma cell lines versus normal thyroid cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Currently there is a lack of effective therapies which result in long-term durable response for patients presenting with anaplastic thyroid carcinoma (ATC), a very rare and lethal variant of thyroid cancer. ATC is resistant to chemotherapy, radiation, and targeted therapies currently available.
In an effort to identify novel tumor-specific therapeutic targets, we performed high throughput gene array analysis screening numerous ATC cell lines, and compared their gene expression levels to normal thyroid cell lines.
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| Overall design |
RNA was extracted from Anaplastic Thyroid Cancer cell lines and Normal Thyroid cell lines. Gene array analysis was performed, and resulting expression levels were compared between Normal and ATC samples
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| Contributor(s) |
Copland J, Weinberger P, Sharma A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 10, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
John A Copland |
| E-mail(s) |
Copland.John@mayo.edu
|
| Organization name |
Mayo Clinic College of Medicine
|
| Department |
Biochemistry & Molecular Biology
|
| Street address |
4500 San Pablo Road
|
| City |
Jacksonville |
| State/province |
FL |
| ZIP/Postal code |
32224 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA338497 |
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