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Status |
Public on Jan 01, 2017 |
Title |
Layer-specific ATAC-seq of the neurons of adult mouse visual cortex defined by Cre-driver lines |
Organism |
Mus musculus |
Experiment type |
Other
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Summary |
Mammalian cortex is a laminar structure, with each layer composed of a characteristic set of cell types with different morphological, electrophysiological, and connectional properties. Here, we define chromatin accessibility landscapes of major, layer-specific excitatory classes of neurons, and compare them to each other and to inhibitory cortical neurons using the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq). We surveyed five Cre-reporter-labeled mouse cell lines using ATAC-Seq of 500-cell populations.
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Overall design |
ATAC-Seq of 500-cell populations
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Contributor(s) |
Gray LT, Yao Z, Nguyen TN, Kim TK, Zeng H, Tasic B |
Citation(s) |
28112643 |
NIH grant(s) |
Grant ID |
Grant title |
Affiliation |
Name |
R01 DA036909 |
Temporal, cell type- and locus-specific epigenetic control in transgenic mice |
ALLEN INSTITUTE |
TASIC |
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Submission date |
Oct 03, 2016 |
Last update date |
May 15, 2019 |
Contact name |
Lucas T Gray |
E-mail(s) |
lucasg@alleninstitute.org
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Organization name |
Allen Institute for Brain Science
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Department |
Molecular Genetics
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Lab |
Tasic
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Street address |
615 Westlake Ave N
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City |
Seattle |
State/province |
WA |
ZIP/Postal code |
98109 |
Country |
USA |
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Platforms (2) |
GPL16417 |
Illumina MiSeq (Mus musculus) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (20)
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Relations |
BioProject |
PRJNA345167 |
SRA |
SRP090744 |