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Series GSE89712 Query DataSets for GSE89712
Status Public on Nov 10, 2016
Title Differential gene expressions in the hypertensive heart using Angiotensin II infusion model
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Differential gene expressions were constructed through expression profiling of a total of 22,556 genes in the hypertensive heart during the early and lately phase of Angiotensin II infusion, then 1019 or 647 significant differential genes were filtered based on the criteria (p<0.05 and fold change >2 or 1.5), respectively.
 
Overall design In the study presented here, the mice were infused Angiotensin II for 0, 7, 28 days (n=2). The hearts were collected and performed transcriptome analysis by RNA-sequencing. Compared to control, 1019 or 537 significant differentially expressed genes (filtering criteria p<0.05, fold change >2.0 for 7 days; fold change >1.5 for 28 days) were identified 7-days or 28 days post-Ang II infusion.
 
Contributor(s) Li Y, Cai W
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Nov 09, 2016
Last update date May 15, 2019
Contact name 李 玉琳
Organization name Beijing Institute of Heart Lung and Blood Vessel Diseases
Street address 2 Anzhen Rd, Chaoyang District,
City Beijing
ZIP/Postal code 100029
Country China
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (6)
GSM2387210 0D-1
GSM2387211 0D-2
GSM2387212 AngII7D-1
Relations
BioProject PRJNA352991
SRA SRP093239

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89712_Anotation_RPKM_.txt.gz 443.1 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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