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Series GSE91402 Query DataSets for GSE91402
Status Public on Jan 01, 2017
Title Molecular distinctions between motor neurons supplying Tibialis anterior (TA), Extensor digitorum longus (EDL), Peroneus longus (PL), Gastrocnemius (GS) and Intrinsic foot (IF) muscles [RNA-seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To probe molecular distinctions in the specification of motor neurons innervating digit muscles we performed a screen for genetic markers that distinguish digit innervating motor neurons from other motor pools. Here, we compare the gene expression profiles of motor neurons that supply muscles with defined biomechanical functions.
Overall design TA, EDL, PL, GS and IF muscles were separately injected at p4 with CTB-555. Pool specific motor neurons were isolated by laser capture from spinal cord sections of p6 wild-type mice. Each pool was profiled by three biological replicates, with each biological replicate containing 30-40 cells from 2-5 animals
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Contributor(s) Mendelsohn AI, Jessell TM
Citation(s) 28190640
Submission date Dec 10, 2016
Last update date May 15, 2019
Contact name Alana Mendelsohn
Organization name Columbia University
Department Department of Biochemistry and Molecular Biophysics
Lab Thomas Jessell
Street address 701 West 168th St
City New York
State/province NY
ZIP/Postal code 10032
Country USA
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (15)
GSM2422856 TA biological rep1
GSM2422857 TA biological rep2
GSM2422858 TA biological rep3
BioProject PRJNA356951
SRA SRP094888

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE91402_EDL_up_v_IF.txt.gz 6.4 Kb (ftp)(http) TXT
GSE91402_EDL_up_v_PL.txt.gz 952 b (ftp)(http) TXT
GSE91402_EDL_up_v_TA.txt.gz 2.3 Kb (ftp)(http) TXT
GSE91402_GS_up_v_IF.txt.gz 4.1 Kb (ftp)(http) TXT
GSE91402_GS_up_v_TA.txt.gz 2.0 Kb (ftp)(http) TXT
GSE91402_IF_up_v_EDL.txt.gz 3.6 Kb (ftp)(http) TXT
GSE91402_IF_up_v_GS.txt.gz 3.5 Kb (ftp)(http) TXT
GSE91402_IF_up_v_PL.txt.gz 898 b (ftp)(http) TXT
GSE91402_IF_up_v_TA.txt.gz 3.6 Kb (ftp)(http) TXT
GSE91402_PL_up_v_EDL.txt.gz 3.1 Kb (ftp)(http) TXT
GSE91402_PL_up_v_IF.txt.gz 2.3 Kb (ftp)(http) TXT
GSE91402_PL_up_v_TA.txt.gz 3.7 Kb (ftp)(http) TXT
GSE91402_TA_up_v_EDL.txt.gz 2.0 Kb (ftp)(http) TXT
GSE91402_TA_up_v_GS.txt.gz 2.0 Kb (ftp)(http) TXT
GSE91402_TA_up_v_IF.txt.gz 5.1 Kb (ftp)(http) TXT
GSE91402_TA_up_v_PL.txt.gz 1.1 Kb (ftp)(http) TXT
GSE91402_gene_levels.tsv.gz 3.0 Mb (ftp)(http) TSV
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Processed data are available on Series record

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