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Series GSE92382 Query DataSets for GSE92382
Status Public on Sep 28, 2017
Title Regulatory remodeling in the allo-tetraploid frog Xenopus laevis
Organisms Xenopus laevis; Xenopus tropicalis; Xenopus tropicalis x Xenopus laevis
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary Genome duplication has played a pivotal role in the evolution of many eukaryotic lineages, including the vertebrates.The most recent vertebrate genome duplication is that in Xenopus laevis, which resulted from the hybridization of two closely related species about 17 million years ago. Here we generated epigenetic profiles and determined gene expression in X.laevis embryos to study the consequences of this duplication at the level of the genome, the epigenome and gene expression.
Overall design Genomic DNA of Xenopus tropicalis and Xenopus laevis; RNA-seq (two replicates) in stage 10.5 Xenopus laevis embryos; ChIP-seq for H3K4me3 and p300 (each two replicates) in Xenopus laevis (LELS), Xenopus tropicalis (TETS) and Xenopus tropicals x laevis (hybrid; LETS) embryos.
Contributor(s) Paranjpe SS, Georgiou G, van Kruijsbergen I, Gibeaux R, Heald R, van Heeringen SJ, Veenstra GC
Citation(s) 29065907, 29320479
Submission date Dec 14, 2016
Last update date May 15, 2019
Contact name Simon van Heeringen
Phone +31-24-3610560
Organization name Radboud University
Department Molecular Developmental Biology
Street address Geert Grooteplein 28
City Nijmegen
ZIP/Postal code 6525GA
Country Netherlands
Platforms (3)
GPL17682 Illumina HiSeq 2000 (Xenopus laevis)
GPL21874 Illumina HiSeq 2000 (Xenopus tropicalis)
GPL22797 Illumina HiSeq 2000 (Xenopus tropicalis x Xenopus laevis)
Samples (22)
GSM2428811 Xenopus_tropicalis_genomic
GSM2428812 Xenopus_laevis_genomic
GSM2428813 Xenopus_laevis_RNAseq_stage10.5_replicate1
BioProject PRJNA357404
SRA SRP095103

Download family Format
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92382_RAW.tar 8.7 Mb (http)(custom) TAR (of BED, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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