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| Status |
Public on Dec 15, 2016 |
| Title |
Esophageal adenocarcinoma gene expression profiling |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression analysis was conducted to determine changes in gene expression and predict signaling networks in esophageal adenocarcinomas. For this analysis we used 12 EAC samples and 9 normal esophageal tissue samples. The analysis indicated deregulation of a large number of genes. Pathway analysis demonstrated the presence of KRAS signature and predicted activation of multiple transcription networks.
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| Overall design |
Expression profile were obtained on 21 Samples (9 normals, and 12 tumors, 9 were tumor-normal pairs) using Affymetrix Human Gene Set St 1.0 arrays.
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| |
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| Contributor(s) |
El-Rifai W, Peng D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 14, 2016 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Yan Guo |
| E-mail(s) |
yanguo1978@gmail.com
|
| Organization name |
Vanderbilt Cancer Center
|
| Street address |
639 Preston Research Bld
|
| City |
Nashville |
| State/province |
TN |
| ZIP/Postal code |
37232 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (22)
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| Relations |
| BioProject |
PRJNA357457 |
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