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Series GSE92416 Query DataSets for GSE92416
Status Public on Dec 15, 2016
Title The Role of a Non-Canonical Splice Variant of the Helios Gene in the Differentiation of Jurkat T Lymphoblasts
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In this study, the ectopic overexpressions of the wild-type Helios-1, non-canonical short isoforms Helios-Δ190-1186, Helios-Δ326-1431, and control in the Jurkat cells were utilized as the routine in vitro model of the T-cell acute lymphoblastic leukemia (T-ALL).
We compared the microarray data for transcriptional analysis of the Jurkat cells with stable overexpression of full-length Helios-1, non-canonical short isoforms Helios-Δ190-1186, Helios-Δ326-1431, and mock transfected control.
 
Overall design Gene expression profiling was performed on Jurkat cells stably expressing Helios-1, as well as short variants Helios-Δ190-1186 and Helios-Δ326-1431.
 
Contributor(s) Feifei L, Yinghui L
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Submission date Dec 14, 2016
Last update date Mar 15, 2019
Contact name Feifei Liu
E-mail(s) feifeink@hotmail.com
Phone 86-15822521698
Organization name Nankai University
Department School of Medicine
Street address 94 Weijin Road
City Tianjin
ZIP/Postal code 300070
Country China
 
Platforms (1)
GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]
Samples (4)
GSM2429529 150602-150072A_MCS_(HuGene-2_0-st)
GSM2429530 150602-150072A_Helios-1_(HuGene-2_0-st)
GSM2429531 150602-150072A_Helios-d190-1186_(HuGene-2_0-st)
Relations
BioProject PRJNA357501

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92416_RAW.tar 33.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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