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Series GSE92539 Query DataSets for GSE92539
Status Public on Dec 08, 2017
Title The histone code reader Spin1 controls skeletal muscle development
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We report developmental defects in Spin1(Myf5-Cre) mice, in which Spin1 is ablated in skeletal muscle.
 
Overall design RNA sequencing of skeletal muscle of Spin1(Myf5-Cre) and control fetuses at E15.5 and E16.5 and of tibialis anterior of surviving Spin1(Myf5-Cre) and control mice at three weeks of age (P21).
ChIP sequencing using primary myoblast isolated from 10-day old mice and anti-SPIN1 antibody (custom SPIN1-5867) or anti-H3K4me antibody (Diagenode, C15410003).
 
Contributor(s) Greschik H, Willmann D, Schüle R
Citation(s) 29168801
Submission date Dec 19, 2016
Last update date May 15, 2019
Contact name Holger Greschik
E-mail(s) holger.greschik@uniklinik-freiburg.de
Organization name University Medical Center Freiburg
Department ZKF
Lab Prof. Roland Schüle
Street address Breisacher Strasse 66
City Freiburg
ZIP/Postal code 79106
Country Germany
 
Platforms (2)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (25)
GSM2432054 E15.5_KO_rep1 (RNA-seq)
GSM2432058 E15.5_KO_rep2 (RNA-seq)
GSM2432060 E15.5_KO_rep3 (RNA-seq)
Relations
BioProject PRJNA357994
SRA SRP095320

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92539_RAW.tar 1.4 Gb (http)(custom) TAR (of BED, WIG)
GSE92539_RNAseq_edgeR_E15_5_3xKO_4xCtrl.xlsx 3.7 Mb (ftp)(http) XLSX
GSE92539_RNAseq_edgeR_E16_5_3xKO_4xCtrl.xlsx 3.7 Mb (ftp)(http) XLSX
GSE92539_RNAseq_edgeR_E16_5_4xCtrl_E15_5_4xCtrl.xlsx 4.2 Mb (ftp)(http) XLSX
GSE92539_RNAseq_edgeR_P21_4xKO_4xCtrl.xlsx 4.0 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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