|
| Status |
Public on Mar 29, 2017 |
| Title |
Whole genome sequencing of murine derived intestinal tumour organoids |
| Organism |
Mus musculus |
| Experiment type |
Genome variation profiling by high throughput sequencing
|
| Summary |
DNA was isolated from Apcmin/+;KrasLSL-G12D/+;VillinCre;Lgr5DTReGFP (AKVL), Apcmin/+;KrasLSL-G12D/+;VillinCre;Lgr5DTReGFP;p53KO (AKVPL) and Apcmin/+;KrasLSL-G12D/+;VillinCre;Lgr5DTReGFP;p53KO,Smad4KO (AKVPSL) organoids as well as the spleen of the AKVL donor animal
The "SAMPLE_ID" sample characteristic is a sample identifier internal to Genentech.
|
| |
|
| Overall design |
Low-coverage (5X) whole genome sequencing of murine derived intestinal organoids containing increasing number of CRC driver mutations
|
| |
|
| Contributor(s) |
Piskol R, de Sousa e Melo F, Kurtova A |
| Citation(s) |
28358093 |
| |
| Submission date |
Dec 27, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Robert Piskol |
| E-mail(s) |
piskolr@gene.com
|
| Organization name |
Genentech Inc.
|
| Department |
gRED Computational Sciences
|
| Street address |
1 DNA Way
|
| City |
South San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94080 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE92966 |
The role of Lgr5 intestinal cancer stem cells in tumour initiation, progression and metastasis |
|
| Relations |
| BioProject |
PRJNA359178 |
| SRA |
SRP095731 |
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