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Sample GSM27161 Query DataSets for GSM27161
Status Public on Nov 05, 2004
Title P328L329_del5a-
Sample type RNA
Source name INS-1 cell line #5a with non-induced HNF1b mutant P328L329del
Organism Rattus norvegicus
Extracted molecule total RNA
Description A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factor can be identified. This entry corresponds to the RNA isolated from uninduced INS-1 cell line #5a containing MODY5 mutant P328L329delCCTCT of hepatocyte nuclear factor-1b (HNF1b).
Keywords = INS-1
Keywords = beta-cell
Keywords = HNF1b
Keywords = P328L329
Keywords = MODY5
Keywords = tetracycline
Keywords = FRT
Submission date Jul 21, 2004
Last update date May 27, 2005
Contact name Ludger Klein-Hitpass
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
Platform ID GPL341
Series (2)
GSE1590 Targets of HNF1b mutants in INS-1
GSE6428 HNF1b, HNF4a2 and HNF6 targets

Data table header descriptions
VALUE ‘signal’, a measure of the abundance of the transcript
ABS_CALL the call in an absolute analysis that indicates whether a transcript is reliably detected (Present, P) or not detected (Absent, A)
DETECTION P-VALUE p-value that indicates the significance level of the detection call

Data table
AFFX-BioB-5_at 255.8 P 0.012547
AFFX-BioB-M_at 400.2 P 0.00034
AFFX-BioB-3_at 102.5 P 0.021902
AFFX-BioC-5_at 608 P 0.00011
AFFX-BioC-3_at 386.8 P 0.000081
AFFX-BioDn-5_at 717 P 0.000662
AFFX-BioDn-3_at 3972.8 P 0.000297
AFFX-CreX-5_at 6541.1 P 0.000044
AFFX-CreX-3_at 12813.9 P 0.000044
AFFX-DapX-5_at 145.3 P 0.000169
AFFX-DapX-M_at 340.4 P 0.004017
AFFX-DapX-3_at 270.2 P 0.000662
AFFX-LysX-5_at 2744 P 0.000044
AFFX-LysX-M_at 3414.5 P 0.000044
AFFX-LysX-3_at 5291.8 P 0.000044
AFFX-PheX-5_at 5250.6 P 0.000044
AFFX-PheX-M_at 5848.8 P 0.000044
AFFX-PheX-3_at 5945.2 P 0.000044
AFFX-ThrX-5_at 787.2 P 0.00006
AFFX-ThrX-M_at 1019.6 P 0.000044

Total number of rows: 15923

Table truncated, full table size 432 Kbytes.

Supplementary data files not provided

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