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Sample GSM27165 Query DataSets for GSM27165
Status Public on Nov 05, 2004
Title P328L329_del6a-
Sample type RNA
Source name INS-1 cell line #6a with non-induced HNF1b mutant P328L329del
Organism Rattus norvegicus
Extracted molecule total RNA
Description A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors can be identified. This entry corresponds to the RNA isolated from uninduced INS-1 cell line #6a containing MODY5 mutant P328L329delCCTCT of hepatocyte nuclear factor-1b (HNF1b).
Keywords = INS-1
Keywords = beta-cell
Keywords = HNF1b
Keywords = P328L329
Keywords = MODY5
Keywords = tetracycline
Keywords = FRT
Submission date Jul 21, 2004
Last update date May 27, 2005
Contact name Ludger Klein-Hitpass
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
Platform ID GPL341
Series (2)
GSE1590 Targets of HNF1b mutants in INS-1
GSE6428 HNF1b, HNF4a2 and HNF6 targets

Data table header descriptions
VALUE ‘signal’, a measure of the abundance of the transcript
ABS_CALL the call in an absolute analysis that indicates whether a transcript is reliably detected (Present, P) or not detected (Absent, A)
DETECTION P-VALUE p-value that indicates the significance level of the detection call

Data table
AFFX-BioB-5_at 308.6 P 0.000754
AFFX-BioB-M_at 628.6 P 0.000147
AFFX-BioB-3_at 162.8 P 0.003212
AFFX-BioC-5_at 722.1 P 0.00007
AFFX-BioC-3_at 386.9 P 0.00011
AFFX-BioDn-5_at 858.7 P 0.000662
AFFX-BioDn-3_at 4631.2 P 0.000169
AFFX-CreX-5_at 7426 P 0.000044
AFFX-CreX-3_at 12278.8 P 0.000044
AFFX-DapX-5_at 181 P 0.000147
AFFX-DapX-M_at 395.1 P 0.003212
AFFX-DapX-3_at 290.8 P 0.00034
AFFX-LysX-5_at 2949.2 P 0.000044
AFFX-LysX-M_at 4173.7 P 0.000044
AFFX-LysX-3_at 6718.1 P 0.000044
AFFX-PheX-5_at 6036.2 P 0.000044
AFFX-PheX-M_at 6771.1 P 0.000044
AFFX-PheX-3_at 7165.6 P 0.000044
AFFX-ThrX-5_at 935.1 P 0.000052
AFFX-ThrX-M_at 1181.6 P 0.000044

Total number of rows: 15923

Table truncated, full table size 431 Kbytes.

Supplementary data files not provided

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