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Sample GSM27167 Query DataSets for GSM27167
Status Public on Nov 05, 2004
Title P328L329_del6a+
Sample type RNA
Source name INS-1 cell line #6a with induced HNF1b mutant P328L329del
Organism Rattus norvegicus
Extracted molecule total RNA
Description A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors can be identified. This entry corresponds to the RNA isolated from tet-induced INS-1 cell line #6a containing MODY5 mutant P328L329delCCTCT of hepatocyte nuclear factor-1b (HNF1b).
Keywords = INS-1
Keywords = beta-cell
Keywords = HNF1b
Keywords = P328L329
Keywords = MODY5
Keywords = tetracycline
Keywords = FRT
Submission date Jul 21, 2004
Last update date May 27, 2005
Contact name Ludger Klein-Hitpass
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
Platform ID GPL341
Series (2)
GSE1590 Targets of HNF1b mutants in INS-1
GSE6428 HNF1b, HNF4a2 and HNF6 targets

Data table header descriptions
VALUE ‘signal’, a measure of the abundance of the transcript
ABS_CALL the call in an absolute analysis that indicates whether a transcript is reliably detected (Present, P) or not detected (Absent, A)
DETECTION P-VALUE p-value that indicates the significance level of the detection call

Data table
AFFX-BioB-5_at 279.1 P 0.00844
AFFX-BioB-M_at 467.8 P 0.000754
AFFX-BioB-3_at 113.8 M 0.054213
AFFX-BioC-5_at 577.9 P 0.000127
AFFX-BioC-3_at 273.4 P 0.000081
AFFX-BioDn-5_at 619.8 P 0.000857
AFFX-BioDn-3_at 4227 P 0.000581
AFFX-CreX-5_at 5643.9 P 0.000044
AFFX-CreX-3_at 10288.1 P 0.000044
AFFX-DapX-5_at 209.1 P 0.00007
AFFX-DapX-M_at 406.3 P 0.003595
AFFX-DapX-3_at 367.4 P 0.000581
AFFX-LysX-5_at 1094.6 P 0.000044
AFFX-LysX-M_at 1382.3 P 0.000044
AFFX-LysX-3_at 2723.8 P 0.000052
AFFX-PheX-5_at 6262.1 P 0.000044
AFFX-PheX-M_at 7104.5 P 0.000044
AFFX-PheX-3_at 7230.6 P 0.000044
AFFX-ThrX-5_at 918.9 P 0.000044
AFFX-ThrX-M_at 1215.2 P 0.000052

Total number of rows: 15923

Table truncated, full table size 432 Kbytes.

Supplementary data files not provided

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