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Sample GSM27170 Query DataSets for GSM27170
Status Public on Nov 05, 2004
Title A263insGG_mut3b+
Sample type RNA
Source name INS-1 cell line #3b with induced HNF1b mutant A263insGG
Organism Rattus norvegicus
Extracted molecule total RNA
Description A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors can be identified. This entry corresponds to the RNA isolated from tet-induced INS-1 cell line #3b containing MODY5 mutant A263insGG of hepatocyte nuclear factor-1b (HNF1b).
Keywords = INS-1
Keywords = beta-cell
Keywords = HNF1b
Keywords = A263insGG
Keywords = MODY5
Keywords = tetracycline
Keywords = FRT
Submission date Jul 21, 2004
Last update date May 27, 2005
Contact name Ludger Klein-Hitpass
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
Platform ID GPL341
Series (2)
GSE1590 Targets of HNF1b mutants in INS-1
GSE6428 HNF1b, HNF4a2 and HNF6 targets

Data table header descriptions
VALUE ‘signal’, a measure of the abundance of the transcript
ABS_CALL the call in an absolute analysis that indicates whether a transcript is reliably detected (Present, P) or not detected (Absent, A)
DETECTION P-VALUE p-value that indicates the significance level of the detection call

Data table
AFFX-BioB-5_at 341.6 P 0.000581
AFFX-BioB-M_at 627.3 P 0.000195
AFFX-BioB-3_at 205.6 P 0.001796
AFFX-BioC-5_at 801.4 P 0.000052
AFFX-BioC-3_at 476.4 P 0.000052
AFFX-BioDn-5_at 1014.1 P 0.000581
AFFX-BioDn-3_at 4467.1 P 0.000258
AFFX-CreX-5_at 7445.8 P 0.000044
AFFX-CreX-3_at 11793 P 0.000044
AFFX-DapX-5_at 84 P 0.000297
AFFX-DapX-M_at 236.8 P 0.004017
AFFX-DapX-3_at 233.5 P 0.000581
AFFX-LysX-5_at 703.3 P 0.000044
AFFX-LysX-M_at 910.8 P 0.000044
AFFX-LysX-3_at 2021.2 P 0.000044
AFFX-PheX-5_at 3912.5 P 0.000044
AFFX-PheX-M_at 4635.3 P 0.000052
AFFX-PheX-3_at 5275.1 P 0.000044
AFFX-ThrX-5_at 666 P 0.00006
AFFX-ThrX-M_at 849.9 P 0.000044

Total number of rows: 15923

Table truncated, full table size 432 Kbytes.

Supplementary data files not provided

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