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Sample GSM3673483 Query DataSets for GSM3673483
Status Public on Nov 18, 2019
Title P16MT1
Sample type SRA
 
Source name Thoracic aortic tissue
Organism Mus musculus
Characteristics strain: C57BL/6J
genotype: Fbn1 mgR/mgR
treatment: no treatment
Extracted molecule total RNA
Extraction protocol none provided by the submitter
 
Library strategy RNA-Seq
Library source transcriptomic
Library selection cDNA
Instrument model Illumina HiSeq 4000
 
Description Fbn1 mgR/mgR mice - age P16
Mice_cuffdiff_results, Mice_cuffdiff_DEGs
Data processing Random read removal from all samples of the same age to correct for read imbalances (after the read removal all samples of the same age have the read count of that sample of that age with the lowest read count)
custom C# script
Alignement to Reference genome
Tophat 2.0.8, samtools-0.1.7, bowtie 2.1.0
Identification of differentially expressed genes
Cufflinks 1.3.0
Genome_build: mm9
Supplementary_files_format_and_content: mouse and human ensemble refernce annotation
Supplementary_files_format_and_content: Mice_cuffdiff_results: cuffdiff output including average gene expression values in whole aortic wall from P16 MFS vs WT mice, baclofen treated P60 WT vs untreated WT mice and baclofen treated P60 MFS vs untreated MFS mice
Supplementary_files_format_and_content: Mice_cuffdiff_DEGs: List of differentially expressed genes in whole aortic wall from P16 MFS vs WT mice, baclofen treated P60 WT vs untreated WT mice and baclofen treated P60 MFS vs untreated MFS mice
 
Submission date Mar 15, 2019
Last update date Nov 18, 2019
Contact name Pauline ARNAUD
Organization name AP-HP - Hôpital Bichat
Street address 46, rue Henri Huchard
City PARIS
ZIP/Postal code 75018
Country France
 
Platform ID GPL21103
Series (1)
GSE128101 Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome
Relations
BioSample SAMN11149045
SRA SRX5527663

Supplementary data files not provided
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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