NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Sample GSM711460 Query DataSets for GSM711460
Status Public on Feb 16, 2012
Title early tumors from fallopian tubes of Dicer/PTEN knockout mice, biological rep 2
Sample type RNA
 
Source name mouse tumor
Organism Mus musculus
Characteristics disease state: ovarian tumor
genotype: Dicer/PTEN KO
Growth protocol We used a mouse genetics strategy to conditionally delete both Dicer and the Pten tumor suppressor in the female reproductive tract using anti-Müllerian hormone receptor type 2 (Amhr2-Cre). These Dicer-Pten DKO (Dicer flox/flox Pten flox/flox Amhr2 cre/+) mice universally develop high-grade serous epithelial cancers.
Extracted molecule total RNA
Extraction protocol Total RNA was extracted using the mirVana miRNA Isolation Kit (ABI). RNA quality were inspected on a 2100 Bioanalyzer (Agilent).
Label biotin
Label protocol According to Illumina protocol.
 
Hybridization protocol According to Illumina protocol.
Scan protocol According to Illumina protocol.
Description early tumors from fallopian tubes of Dicer/PTEN knockout mice, biological rep 2
Data processing The image data were compiled into a project using Beadstudio software gene expression module version 3.2.7. No normalization was used. The data was exported as txt files using the build-in function of export to GeneSpring GX format. The option of sample probe profile was chosen. Data were subsequently quantile normalized for the analysis.
 
Submission date Apr 19, 2011
Last update date Feb 16, 2012
Contact name Chad Creighton
E-mail(s) creighto@bcm.tmc.edu
Organization name Baylor College of Medicine
Department Biostatistics, Ducan Cancer Center
Street address One Baylor Plaza, Mail Stop: BCM305
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
 
Platform ID GPL6887
Series (2)
GSE28720 Gene expression analysis of ovarian tumors from mice with knockout of DICER and PTEN
GSE28979 Gene expression profiles of serous ovarian cancer in human and mouse

Data table header descriptions
ID_REF
VALUE 'signal' a measure of the abundance of a transcript

Data table
ID_REF VALUE
ILMN_2735294 80.0257
ILMN_2417611 39.9
ILMN_2545897 98.1075
ILMN_2762289 55.5714
ILMN_1248788 65.375
ILMN_2707227 72.3842
ILMN_2896528 849.9216
ILMN_2721178 205.2442
ILMN_1227723 457.0702
ILMN_2458837 46.2
ILMN_3033922 1052.841
ILMN_3092673 4003.4253
ILMN_1230777 2527.1095
ILMN_2730714 6561.476
ILMN_1246069 2389.9589
ILMN_1232042 55.9143
ILMN_1243193 917.3508
ILMN_2524361 60.7889
ILMN_1233188 185.8283
ILMN_2543688 1242.3082

Total number of rows: 45281

Table truncated, full table size 899 Kbytes.




Supplementary file Size Download File type/resource
GSM711460.txt.gz 671.8 Kb (ftp)(http) TXT
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap