U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    OR6A2 olfactory receptor family 6 subfamily A member 2 [ Homo sapiens (human) ]

    Gene ID: 8590, updated on 2-Nov-2024

    Summary

    Official Symbol
    OR6A2provided by HGNC
    Official Full Name
    olfactory receptor family 6 subfamily A member 2provided by HGNC
    Primary source
    HGNC:HGNC:15301
    See related
    Ensembl:ENSG00000184933 MIM:608495; AllianceGenome:HGNC:15301
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    I7; OR6A1; OR6A2P; OR11-55
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See OR6A2 in Genome Data Viewer
    Location:
    11p15.4
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (6791736..6799689, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6850158..6858111, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6812967..6820920, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily AG member 2 Neighboring gene olfactory receptor family 2 subfamily AG member 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:6821660-6822576 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:6822577-6823492 Neighboring gene phosphorylated adaptor for RNA export pseudogene Neighboring gene olfactory receptor family 10 subfamily A member 5

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC126538, MGC126540

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sensory perception of smell NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in signal transduction NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 6A2
    Names
    hI7 olfactory receptor
    hP2 olfactory receptor
    olfactory receptor 11-55
    olfactory receptor 6A1
    olfactory receptor OR11-83
    olfactory receptor, family 6, subfamily A, member 1
    olfactory receptor, family 6, subfamily A, member 2 pseudogene
    seven transmembrane helix receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_003696.3NP_003687.2  olfactory receptor 6A2

      See identical proteins and their annotated locations for NP_003687.2

      Status: VALIDATED

      Source sequence(s)
      AC087280
      Consensus CDS
      CCDS7772.1
      UniProtKB/Swiss-Prot
      O95222, Q3MJC7, Q6IF35, Q9H206
      UniProtKB/TrEMBL
      A0A126GW91
      Related
      ENSP00000492990.1, ENST00000641196.1
      Conserved Domains (1) summary
      cd15224
      Location:41299
      7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      6791736..6799689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      6850158..6858111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)