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    DDR2 Ddr2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854104, updated on 29-Jun-2024

    Summary

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    Gene symbol
    DDR2
    Gene description
    Ddr2p
    Primary source
    FungiDB:YOL052C-A
    Locus tag
    YOL052C-A
    See related
    SGD:S000005413; AllianceGenome:SGD:S000005413; VEuPathDB:YOL052C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YOL053C-A
    Summary
    Involved in several processes, including cellular response to heat; cellular response to hydrogen peroxide; and cellular response to starvation. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See DDR2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (231570..231755, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase PSH1 Neighboring gene Aim39p Neighboring gene adenosylmethionine decarboxylase SPE2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and functional analysis of the multistress response gene DDR2 from Saccharomyces cerevisiae. Kobayashi N, et al. Biochem Biophys Res Commun, 1996 Dec 13. PMID 8954934
    2. Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae. Kobayashi N, et al. Mol Cell Biol, 1993 Jan. PMID 8417330, Free PMC Article
    3. Evidence for a heat shock transcription factor-independent mechanism for heat shock induction of transcription in Saccharomyces cerevisiae. Kobayashi N, et al. Proc Natl Acad Sci U S A, 1990 Sep. PMID 2118651, Free PMC Article
    4. Functional analysis of the stress response element and its role in the multistress response of Saccharomyces cerevisiae. Treger JM, et al. Biochem Biophys Res Commun, 1998 Feb 4. PMID 9473471
    5. Transcriptional regulation of DNA damage responsive (DDR) genes in different rad mutant strains of Saccharomyces cerevisiae. Maga JA, et al. Mol Gen Genet, 1986 Nov. PMID 3100912

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Ddr2p
    NP_014589.1
    • Multi-stress response protein; expression is activated by a variety of xenobiotic agents and environmental or physiological stresses; DDR2 has a paralog, HOR7, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      231570..231755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183307.1 → NP_014589.1  TPA: Ddr2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014589.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W215, P89113
      UniProtKB/TrEMBL
      A0A6A5Q406, A6ZNF8, B3LJ07, C7GK19, C8ZHR1, G2WMI2, N1NWQ5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P89113.1

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