Rps23 ribosomal protein S23 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rps23provided by RGD
Official Full Name: ribosomal protein S23provided by RGD
Primary source: RGD:621039
See related: EnsemblRapid:ENSRNOG00000016580 AllianceGenome:RGD:621039
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis; stress granule assembly; and translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Spleen (RPKM 7904.4), Thymus (RPKM 5956.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (23814517..23816087)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (22079339..22080909)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (19823234..19824804)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	ISO Inferred from Sequence Orthology more info
enables structural constituent of ribosome	ISS Inferred from Sequence or Structural Similarity more info
enables translation regulator activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cytoplasmic translation	IEA Inferred from Electronic Annotation more info
involved_in cytoplasmic translation	ISO Inferred from Sequence Orthology more info
involved_in cytoplasmic translation	ISS Inferred from Sequence or Structural Similarity more info
involved_in maintenance of translational fidelity	IEA Inferred from Electronic Annotation more info
involved_in maintenance of translational fidelity	ISO Inferred from Sequence Orthology more info
involved_in maintenance of translational fidelity	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in ribosomal small subunit biogenesis	IEA Inferred from Electronic Annotation more info
involved_in ribosomal small subunit biogenesis	ISO Inferred from Sequence Orthology more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in stress granule assembly	IEA Inferred from Electronic Annotation more info
involved_in stress granule assembly	ISO Inferred from Sequence Orthology more info
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	ISO Inferred from Sequence Orthology more info
involved_in translation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasmic side of rough endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in cytosolic ribosome	ISO Inferred from Sequence Orthology more info
part_of cytosolic small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic small ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic small ribosomal subunit	IEA Inferred from Electronic Annotation more info
part_of cytosolic small ribosomal subunit	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
is_active_in ribosome	IBA Inferred from Biological aspect of Ancestor more info
located_in ribosome	NAS Non-traceable Author Statement more info	PubMed
located_in rough endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
part_of small ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of small-subunit processome	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info
is_active_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small ribosomal subunit protein uS12

Names: 40S ribosomal protein S23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.