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    Mgarp mitochondria-localized glutamic acid-rich protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689931, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mgarpprovided by RGD
    Official Full Name
    mitochondria-localized glutamic acid-rich proteinprovided by RGD
    Primary source
    RGD:1586369
    See related
    EnsemblRapid:ENSRNOG00000011923 AllianceGenome:RGD:1586369
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Osap
    Summary
    Predicted to be involved in several processes, including axonal transport; cellular response to gonadotropin-releasing hormone; and nervous system development. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to human MGARP (mitochondria localized glutamic acid rich protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 2288.6) See more
    Orthologs
    NEW
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    Genomic context

    See Mgarp in Genome Data Viewer
    Location:
    2q26
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (137582152..137590294, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (135431283..135439425, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (140444963..140453719, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon UGG) 2 Neighboring gene transfer RNA proline (anticodon AGG) 4 Neighboring gene NADH:ubiquinone oxidoreductase subunit C1 Neighboring gene uncharacterized LOC134485908

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in anterograde axonal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axon development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axonal transport of mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to gonadotropin-releasing hormone ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to steroid hormone stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cerebral cortex development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of dendrite development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrion organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in retrograde axonal transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in axon cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein MGARP
    Names
    hypoxia up-regulated mitochondrial movement regulator
    ovary-specific acidic protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109556.1NP_001103026.1  protein MGARP

      See identical proteins and their annotated locations for NP_001103026.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474003
      UniProtKB/TrEMBL
      A6JV58, D4A4W7
      Related
      ENSRNOP00000016475.5, ENSRNOT00000016475.7
      Conserved Domains (1) summary
      pfam14962
      Location:1193
      AIF-MLS; Mitochondria Localization Sequence

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      137582152..137590294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)