Mgarp mitochondria-localized glutamic acid-rich protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mgarpprovided by RGD
Official Full Name: mitochondria-localized glutamic acid-rich proteinprovided by RGD
Primary source: RGD:1586369
See related: EnsemblRapid:ENSRNOG00000011923 AllianceGenome:RGD:1586369
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Osap
Summary: Predicted to be involved in several processes, including axonal transport; cellular response to gonadotropin-releasing hormone; and nervous system development. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to human MGARP (mitochondria localized glutamic acid rich protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 2288.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 2q26

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (137582152..137590294, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (135431283..135439425, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (140444963..140453719, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in anterograde axonal transport	ISO Inferred from Sequence Orthology more info
involved_in axon development	ISO Inferred from Sequence Orthology more info
involved_in axonal transport of mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in cellular response to gonadotropin-releasing hormone	ISO Inferred from Sequence Orthology more info
involved_in cellular response to hypoxia	ISO Inferred from Sequence Orthology more info
involved_in cellular response to steroid hormone stimulus	ISO Inferred from Sequence Orthology more info
involved_in cerebral cortex development	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of dendrite development	ISO Inferred from Sequence Orthology more info
involved_in protein targeting to mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitochondrion organization	ISO Inferred from Sequence Orthology more info
involved_in retrograde axonal transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in axon cytoplasm	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein MGARP

Names: hypoxia up-regulated mitochondrial movement regulator; ovary-specific acidic protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.