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    Tmem254 transmembrane protein 254 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290529, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Tmem254provided by RGD
    Official Full Name
    transmembrane protein 254provided by RGD
    Primary source
    RGD:1305689
    See related
    EnsemblRapid:ENSRNOG00000011276 AllianceGenome:RGD:1305689
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam213a; RGD1305689
    Summary
    Predicted to be integral component of membrane. Orthologous to human TMEM254 (transmembrane protein 254). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 109.4), Thymus (RPKM 62.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem254 in Genome Data Viewer
    Location:
    16p16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (1510705..1514591, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (1503931..1507819, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (3817402..3821270)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene placenta associated 9 Neighboring gene uncharacterized LOC134482312 Neighboring gene cytoplasmic polyadenylated homeobox 1 Neighboring gene double homeobox 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105674

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 254
    Names
    family with sequence similarity 213, member A
    homolog of C10orf57
    transmembrane protein C10orf57 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008297.1 → NP_001008298.1  transmembrane protein 254

      See identical proteins and their annotated locations for NP_001008298.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086323
      UniProtKB/Swiss-Prot
      Q5U220
      UniProtKB/TrEMBL
      A6KMI5
      Conserved Domains (1) summary
      pfam14934
      Location:26 → 112
      DUF4499; Domain of unknown function (DUF4499)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      1510705..1514591 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252573.4 → XP_006252635.1  transmembrane protein 254 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWQ4
      Related
      ENSRNOP00000069971.1, ENSRNOT00000088566.3
      Conserved Domains (1) summary
      pfam14934
      Location:32 → 118
      DUF4499; Domain of unknown function (DUF4499)

    2. XM_039094246.2 → XP_038950174.1  transmembrane protein 254 isoform X2

      Conserved Domains (1) summary
      pfam14934
      Location:5 → 87
      DUF4499; Domain of unknown function (DUF4499)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U220.1 GenPept UniProtKB/Swiss-Prot:Q5U220

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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