U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CXorf58 chromosome X open reading frame 58 [ Homo sapiens (human) ]

    Gene ID: 254158, updated on 10-Oct-2024

    Summary

    Official Symbol
    CXorf58provided by HGNC
    Official Full Name
    chromosome X open reading frame 58provided by HGNC
    Primary source
    HGNC:HGNC:26356
    See related
    Ensembl:ENSG00000165182 AllianceGenome:HGNC:26356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in testis (RPKM 2.2) and thyroid (RPKM 0.1) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CXorf58 in Genome Data Viewer
    Location:
    Xp22.11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (23907932..23939509)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (23491609..23523191)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (23926123..23957626)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:23800811-23802010 Neighboring gene uncharacterized LOC127933115 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chrX:23825194-23826393 Neighboring gene spermidine/spermine N1-acetyltransferase 1 Neighboring gene ribosomal protein L9 pseudogene 7 Neighboring gene apolipoprotein O Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:23900936-23901702 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:23905519-23905696 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29494 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:23970710-23971248 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:23971249-23971786 Neighboring gene Sharpr-MPRA regulatory region 13558 Neighboring gene kelch like family member 15 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29495 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20708 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20709 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20710 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:24043667-24044171 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:24044172-24044675 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:24045883-24046382 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29497 Neighboring gene eukaryotic translation initiation factor 2 subunit gamma

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein CXorf58

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016380.1 RefSeqGene

      Range
      5001..36504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169574.2NP_001163045.1  uncharacterized protein CXorf58 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC079376, AK058173, BC144007
      UniProtKB/TrEMBL
      B7ZLS7
    2. NM_152761.3NP_689974.2  uncharacterized protein CXorf58 isoform 1

      See identical proteins and their annotated locations for NP_689974.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC079376, AK058173
      Consensus CDS
      CCDS14209.1
      UniProtKB/Swiss-Prot
      Q96LI9
      UniProtKB/TrEMBL
      B7ZLS7
      Related
      ENSP00000368511.3, ENST00000379211.8

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      23907932..23939509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011545473.3XP_011543775.1  uncharacterized protein CXorf58 isoform X1

      See identical proteins and their annotated locations for XP_011543775.1

      UniProtKB/Swiss-Prot
      Q96LI9
      UniProtKB/TrEMBL
      B7ZLS7
    2. XM_011545474.3XP_011543776.1  uncharacterized protein CXorf58 isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      23491609..23523191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054326756.1XP_054182731.1  uncharacterized protein CXorf58 isoform X1

    2. XM_054326757.1XP_054182732.1  uncharacterized protein CXorf58 isoform X2