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    C22orf42 chromosome 22 open reading frame 42 [ Homo sapiens (human) ]

    Gene ID: 150297, updated on 17-Sep-2024

    Summary

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    Official Symbol
    C22orf42provided by HGNC
    Official Full Name
    chromosome 22 open reading frame 42provided by HGNC
    Primary source
    HGNC:HGNC:27160
    See related
    Ensembl:ENSG00000205856 AllianceGenome:HGNC:27160
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    dJ90G24.6
    Expression
    Restricted expression toward testis (RPKM 3.7) See more
    Orthologs
    all
    NEW
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    Genomic context

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    See C22orf42 in Genome Data Viewer
    Location:
    22q12.3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (32149006..32160448, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (32613084..32624526, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (32544993..32555290, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:32519556-32520056 Neighboring gene AP1B1 pseudogene 1 Neighboring gene AP1B1 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:32602504-32603234 Neighboring gene SLC5A4 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:32608089-32608590 Neighboring gene ret finger protein like 2 Neighboring gene solute carrier family 5 member 4 Neighboring gene CPSF1 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins. Sivertsson Å, et al. J Proteome Res, 2020 Dec 4. PMID 33170010, Free PMC Article
    2. Identification of Human N-Myristoylated Proteins from Human Complementary DNA Resources by Cell-Free and Cellular Metabolic Labeling Analyses. Takamitsu E, et al. PLoS One, 2015. PMID 26308446, Free PMC Article
    3. A proteome-scale map of the SARS-CoV-2-human contactome. Kim DK, et al. Nat Biotechnol, 2023 Jan. PMID 36217029, Free PMC Article
    4. A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802, Free PMC Article
    5. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy. Sun X, et al. Acta Pharm Sin B, 2022 Feb. PMID 35256949, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    uncharacterized protein C22orf42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010859.3 → NP_001010859.1  uncharacterized protein C22orf42

      See identical proteins and their annotated locations for NP_001010859.1

      Status: VALIDATED

      Source sequence(s)
      AL008723, BU072847, CK818305, CR456485
      Consensus CDS
      CCDS33639.1
      UniProtKB/Swiss-Prot
      A4QPH5, Q6IC83
      Related
      ENSP00000371529.3, ENST00000382097.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      32149006..32160448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017028630.3 → XP_016884119.1  uncharacterized protein C22orf42 isoform X3

    2. XM_011529922.4 → XP_011528224.1  uncharacterized protein C22orf42 isoform X1

    3. XM_017028629.3 → XP_016884118.1  uncharacterized protein C22orf42 isoform X2

    4. XM_017028631.2 → XP_016884120.1  uncharacterized protein C22orf42 isoform X4

    5. XM_017028632.3 → XP_016884121.1  uncharacterized protein C22orf42 isoform X5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      32613084..32624526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054325145.1 → XP_054181120.1  uncharacterized protein C22orf42 isoform X6

    2. XM_054325146.1 → XP_054181121.1  uncharacterized protein C22orf42 isoform X7

    3. XM_054325148.1 → XP_054181123.1  uncharacterized protein C22orf42 isoform X2

    4. XM_054325147.1 → XP_054181122.1  uncharacterized protein C22orf42 isoform X8

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6IC83.1 GenPept UniProtKB/Swiss-Prot:Q6IC83

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