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    Zfp940 zinc finger protein 940 [ Mus musculus (house mouse) ]

    Gene ID: 233057, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Zfp940provided by MGI
    Official Full Name
    zinc finger protein 940provided by MGI
    Primary source
    MGI:MGI:2446235
    See related
    Ensembl:ENSMUSG00000050855 AllianceGenome:MGI:2446235
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 3.0), cerebellum adult (RPKM 2.4) and 17 other tissues See more
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    Genomic context

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    See Zfp940 in Genome Data Viewer
    Location:
    7 B1; 7 17.26 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29533943..29553101, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29832361..29853695, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18490 Neighboring gene predicted gene 6579 Neighboring gene STARR-seq mESC enhancer starr_18491 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30601028-30601137 Neighboring gene zinc finger protein 790 Neighboring gene STARR-positive B cell enhancer ABC_E8836 Neighboring gene STARR-positive B cell enhancer ABC_E10434 Neighboring gene zinc finger protein 420 Neighboring gene STARR-seq mESC enhancer starr_18494 Neighboring gene zinc finger protein 27 Neighboring gene microRNA 7668

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 940

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419283.1 → NP_001406212.1  zinc finger protein 940 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC156934
      UniProtKB/TrEMBL
      Q8R2Q3

    2. NM_001419284.1 → NP_001406213.1  zinc finger protein 940 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC156934
      UniProtKB/TrEMBL
      Q8R2Q3

    3. NM_001419285.1 → NP_001406214.1  zinc finger protein 940 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC156934
      UniProtKB/TrEMBL
      Q3UVK2
      Related
      ENSMUSP00000103858.2, ENSMUST00000108223.8

    4. NM_173738.3 → NP_776099.1  zinc finger protein 940 isoform 1

      See identical proteins and their annotated locations for NP_776099.1

      Status: VALIDATED

      Source sequence(s)
      AC156934
      Consensus CDS
      CCDS39873.1
      UniProtKB/TrEMBL
      Q3V1P9, Q8R2Q3
      Related
      ENSMUSP00000082947.5, ENSMUST00000085792.5
      Conserved Domains (4) summary
      smart00349
      Location:6 → 66
      KRAB; krueppel associated box
      COG5048
      Location:249 → 437
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:398 → 418
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:342 → 357
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29533943..29553101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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