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    MUP3 Mup3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856349, updated on 2-Nov-2024

    Summary

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    Official Symbol
    MUP3
    Official Full Name
    Mup3p
    Primary source
    SGD:S000001028
    Locus tag
    YHL036W
    See related
    AllianceGenome:SGD:S000001028; FungiDB:YHL036W; VEuPathDB:YHL036W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables L-methionine transmembrane transporter activity. Involved in methionine import across plasma membrane. Located in fungal-type vacuole. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; hepatocellular carcinoma; and lung squamous cell carcinoma. Orthologous to several human genes including SLC7A13 (solute carrier family 7 member 13). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See MUP3 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (26241..27881)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Cbp2p Neighboring gene uncharacterized protein Neighboring gene putative ATP-binding cassette multidrug transporter VMR1 Neighboring gene Sbp1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-methionine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables L-methionine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methionine import across plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in methionine import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mup3p
    NP_011827.1
    • Low affinity methionine permease; similar to Mup1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      26241..27881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179116.1 → NP_011827.1  TPA: Mup3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011827.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKT2, P38734
      UniProtKB/TrEMBL
      A6ZSL4, B3LS83, B5VJP0, C8ZA26, G2WF29, N1P545
      Conserved Domains (1) summary
      TIGR00911
      Location:40 → 538
      2A0308; L-type amino acid transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38734.1

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