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    Klhdc9 kelch domain containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 68874, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Klhdc9provided by MGI
    Official Full Name
    kelch domain containing 9provided by MGI
    Primary source
    MGI:MGI:1916124
    See related
    Ensembl:ENSMUSG00000045259 AllianceGenome:MGI:1916124
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ESTM31; 1190002J23Rik
    Summary
    Predicted to enable cyclin binding activity. Orthologous to human KLHDC9 (kelch domain containing 9). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 5.0), cortex adult (RPKM 4.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Klhdc9 in Genome Data Viewer
    Location:
    1 H3; 1 79.36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (171186017..171188366, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (171358449..171360798, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 20045 Neighboring gene death effector domain-containing Neighboring gene STARR-positive B cell enhancer ABC_E2019 Neighboring gene nitrilase 1 Neighboring gene prefoldin 2 Neighboring gene STARR-positive B cell enhancer ABC_E4387 Neighboring gene nectin cell adhesion molecule 4 Neighboring gene STARR-positive B cell enhancer ABC_E4388 Neighboring gene Rho GTPase activating protein 30 Neighboring gene STARR-positive B cell enhancer ABC_E4389

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Eddleston J, et al. Genomics, 1999 Mar 1. PMID 10051400
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cyclin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    kelch domain-containing protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033039.2 → NP_001028211.1  kelch domain-containing protein 9

      See identical proteins and their annotated locations for NP_001028211.1

      Status: PROVISIONAL

      Source sequence(s)
      AK140290
      Consensus CDS
      CCDS35776.1
      UniProtKB/Swiss-Prot
      Q3USL1, Q8BVR4
      UniProtKB/TrEMBL
      B2RUK8
      Related
      ENSMUSP00000056212.5, ENSMUST00000061878.5
      Conserved Domains (3) summary
      sd00038
      Location:28 → 76
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:79 → 118
      Kelch_1; Kelch motif
      pfam13854
      Location:256 → 296
      Kelch_5; Kelch motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      171186017..171188366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3USL1.1 GenPept UniProtKB/Swiss-Prot:Q3USL1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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