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    LINC01605 long intergenic non-protein coding RNA 1605 [ Homo sapiens (human) ]

    Gene ID: 100507420, updated on 17-Jun-2024

    Summary

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    Official Symbol
    LINC01605provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1605provided by HGNC
    Primary source
    HGNC:HGNC:51654
    See related
    Ensembl:ENSG00000253414 AllianceGenome:HGNC:51654
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ODIR1; LincDUSP
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC01605 in Genome Data Viewer
    Location:
    8p11.23
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (37403516..37599839, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (37678855..37875158, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (37261034..37457357, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100507403 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:37188590-37189789 Neighboring gene uncharacterized LOC124901930 Neighboring gene VISTA enhancer hs302 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27225 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37310647-37311224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37374880-37375400 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37375401-37375919 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:37378682-37379881 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:37387319-37387531 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37400987-37401487 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37404685-37405219 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37405335-37405836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37405837-37406336 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37413320-37413920 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:37417549-37418050 Neighboring gene uncharacterized LOC105379379 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:37418051-37418550 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37438583-37439182 Neighboring gene uncharacterized LOC105379378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37439183-37439782 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:37452253-37453174 Neighboring gene uncharacterized LOC105379380 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37462486-37462996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37467873-37468422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:37468423-37468972 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27227 Neighboring gene uncharacterized LOC124901931 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:37494669-37495193 Neighboring gene VISTA enhancer hs834 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:37496445-37496652 Neighboring gene RNA, U6 small nuclear 607, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer. Wang W, et al. Cancer Sci, 2022 Aug. PMID 35411612, Free PMC Article
    2. Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis. Forrest ME, et al. Sci Rep, 2018 May 9. PMID 29743621, Free PMC Article
    3. LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p. Wang XY, et al. Eur Rev Med Pharmacol Sci, 2019 Dec. PMID 31841192
    4. LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11. Hu SS, et al. Eur Rev Med Pharmacol Sci, 2021 Feb. PMID 33629302
    5. LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis. He S, et al. Cell Death Dis, 2019 Dec 11. PMID 31827076, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis.
      Title: LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis.
    2. LINC01605 Is a Novel Target of Mutant p53 in Breast and Ovarian Cancer Cell Lines.
      Title: LINC01605 Is a Novel Target of Mutant p53 in Breast and Ovarian Cancer Cell Lines.
    3. LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer.
      Title: LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer.
    4. LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11.
      Title: LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11.
    5. LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
      Title: LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
    6. key role of lincDUSP in the regulation of important pathways in colon cancer
      Title: Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • RP11-527N22.2
    • TCONS_00014973
    • osteogenic differentiation inhibitory regulator 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_121620.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    2. NR_121621.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124067
      Related
      ENST00000668286.1

    3. NR_170186.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    4. NR_170187.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124067

    5. NR_170188.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124067

    6. NR_170189.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    7. NR_170190.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    8. NR_170191.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    9. NR_170192.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    10. NR_170193.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    11. NR_170194.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007590, AC091182, AC124067

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      37403516..37599839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      37678855..37875158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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