U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    LSP1P5 LSP1 pseudogene 5 [ Homo sapiens (human) ]

    Gene ID: 645166, updated on 29-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    LSP1P5provided by HGNC
    Official Full Name
    LSP1 pseudogene 5provided by HGNC
    Primary source
    HGNC:HGNC:50697
    See related
    Ensembl:ENSG00000288905 AllianceGenome:HGNC:50697
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in placenta (RPKM 6.5), urinary bladder (RPKM 4.2) and 23 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LSP1P5 in Genome Data Viewer
    Location:
    1q21.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (144716079..144740806)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (143326556..143351287, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (148928313..148953054)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 2C pseudogene 1 Neighboring gene dopamine receptor D5 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 59 Neighboring gene Sharpr-MPRA regulatory region 154 duplicate 3 Neighboring gene proton channel OTOP1-like Neighboring gene uncharacterized LOC105371216

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains. Yu HC, et al. Front Immunol, 2021. PMID 33717069, Free PMC Article
    2. Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids. Gu S, et al. Mol Ther, 2024 Jun 5. PMID 38553852,
    3. Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family. May W, et al. Genomics, 1993 Mar. PMID 8468046
    4. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.
      Title: Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.
    2. Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-kappaB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains.
      Title: Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains.
    Submit: New GeneRIF Correction

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See Variation Viewer (GRCh37.p13)

    General gene information

    Go to the top of the page Help

    Markers

    Clone Names

    • FLJ18771

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027354.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AK311729, FP700111

    2. NR_027355.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' exon and an alternate 3' exon, compared to variant 1.
      Source sequence(s)
      AI087158, AK311729, BE814857, BG716766, DA808118
      Related
      ENST00000690033.3

    3. NR_027356.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has alternate 5' and 3' exons and lacks an internal alternate exon, compared to variant 1.
      Source sequence(s)
      AI087158, AK311729, AW954772, DA808118
      Related
      ENST00000686318.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      144716079..144740806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      143326556..143351287 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials