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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001258290.2 → NP_001245219.1 polyserase-2 isoform 2 precursor
See identical proteins and their annotated locations for NP_001245219.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
- Source sequence(s)
-
AC009088, AI864473, AK290310, AK297997, BC144615
- Consensus CDS
-
CCDS58453.1
- UniProtKB/Swiss-Prot
-
Q5K4E3
- UniProtKB/TrEMBL
-
B4DNP1
- Related
- ENSP00000454768.1, ENST00000569305.1
- Conserved Domains (3) summary
-
- smart00020
Location:46 → 286
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:47 → 289
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- cl21584
Location:596 → 778
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_001258291.2 → NP_001245220.1 polyserase-2 isoform 3 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
- Source sequence(s)
-
AC009088, AI864473, AK290310, AK297997, AK301409
- Consensus CDS
-
CCDS58452.1
- UniProtKB/Swiss-Prot
-
Q5K4E3
- UniProtKB/TrEMBL
-
B4DNP1
- Related
- ENSP00000407160.2, ENST00000418068.6
- Conserved Domains (3) summary
-
- smart00020
Location:46 → 286
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:47 → 289
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- cl21584
Location:330 → 538
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_173502.5 → NP_775773.2 polyserase-2 isoform 1 precursor
See identical proteins and their annotated locations for NP_775773.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AC009088, AI864473, AK290310, AK297997
- Consensus CDS
-
CCDS32436.1
- UniProtKB/Swiss-Prot
- A8K2P5, B4DW80, B7ZMK8, E7EX56, Q5K4E3, Q8NBY4
- Related
- ENSP00000268281.4, ENST00000268281.9
- Conserved Domains (3) summary
-
- smart00020
Location:46 → 286
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:47 → 289
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- cl21584
Location:330 → 538
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000016.10 Reference GRCh38.p14 Primary Assembly
- Range
-
31138926..31150066 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017022971.2 → XP_016878460.1 polyserase-2 isoform X2
-
XM_017022968.2 → XP_016878457.1 polyserase-2 isoform X1
- Conserved Domains (2) summary
-
- cd00190
Location:47 → 289
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- cl21584
Location:330 → 538
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Alternate T2T-CHM13v2.0
Genomic
-
NC_060940.1 Alternate T2T-CHM13v2.0
- Range
-
31526407..31537545 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054379684.1 → XP_054235659.1 polyserase-2 isoform X2
-
XM_054379683.1 → XP_054235658.1 polyserase-2 isoform X1