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    noxC water forming NADH oxidase (nitroreductase) [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 939506, updated on 12-Feb-2021

    Summary

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    Gene symbol
    noxC
    Gene description
    water forming NADH oxidase (nitroreductase)
    Locus tag
    BSU_19550
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU19550
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    Genomic context

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    Sequence:
    NC_000964.3 (2127813..2128421)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene putative tautomerase Neighboring gene transcriptional repressor Neighboring gene putative hydrolase Neighboring gene putative thiol-dependent lyase/dioxygenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis. Zhang X, et al. Metab Eng, 2014 May. PMID 24525333
    2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
    3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
    4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
    5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Moderate-expression of YODC in the bdhA disrupted B. subtilis weakened the NADH-linked pathways to by-product pools of acetoin.
      Title: The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    water forming NADH oxidase (nitroreductase)
    NP_389836.1
    • Evidence 1b: Function from experimental evidences in the studied species; PubMedId: 21749987, 24525333, 26312069; Product type e: enzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_389836.1 water forming NADH oxidase (nitroreductase) [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_389836.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P81102
      Conserved Domains (1) summary
      cd02137
      Location:5 → 198
      MhqN-like; nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P81102.3

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases