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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_033804.1 RefSeqGene
- Range
-
2869..263764
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001170637.4 → NP_001164108.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform c
See identical proteins and their annotated locations for NP_001164108.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate in-frame splice site compared to variant 1. The encoded isoform (c) is shorter than isoform a.
- Source sequence(s)
-
AB007925, AC244034, AC244035, AK294060, BC063527, BC144343, DA110905
- Consensus CDS
-
CCDS76262.1
- UniProtKB/TrEMBL
- B7ZM87, Q5VZB5
- Related
- ENSP00000485517.1, ENST00000624873.3
- Conserved Domains (4) summary
-
- cd07682
Location:26 → 288
- F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
- PHA03269
Location:962 → 1064
- PHA03269; envelope glycoprotein C; Provisional
- cd11955
Location:731 → 783
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:486 → 673
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
-
NM_001300952.2 → NP_001287881.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform d
See identical proteins and their annotated locations for NP_001287881.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice site and differs in the 3' exon structure, result in a different 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (d) has a distinct C-terminus and is shorter than isoform a.
- Source sequence(s)
-
AC244023, AC244035, AK057565, AK295845, BC041635, CA447513, DA110905
- Consensus CDS
-
CCDS76261.1
- UniProtKB/TrEMBL
- A0A075B7B5, B7Z3G4
- Related
- ENSP00000473954.1, ENST00000605610.5
- Conserved Domains (3) summary
-
- cd11955
Location:731 → 783
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:486 → 673
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:26 → 288
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
-
NM_001377444.1 → NP_001364373.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform e
Status: REVIEWED
- Source sequence(s)
-
AC244023, AC244034, AC244035
- UniProtKB/TrEMBL
- A0A1S5UZH8, B7Z3G4
- Conserved Domains (3) summary
-
- cd11955
Location:732 → 784
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:487 → 674
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:26 → 289
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
-
NM_001377445.1 → NP_001364374.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform f
Status: REVIEWED
- Source sequence(s)
-
AC244023, AC244034, AC244035
- UniProtKB/TrEMBL
-
B7Z3G4
- Conserved Domains (3) summary
-
- cd11955
Location:732 → 784
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:487 → 674
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:26 → 289
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
-
NM_001377446.1 → NP_001364375.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform g
Status: REVIEWED
- Source sequence(s)
-
AC244023, AC244034, AC244035
- UniProtKB/TrEMBL
-
B7Z3G4
- Conserved Domains (3) summary
-
- cd11955
Location:731 → 783
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:486 → 673
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:26 → 288
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
-
NM_001377447.1 → NP_001364376.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform h
Status: REVIEWED
- Source sequence(s)
-
AC244023, AC244034, AC244035
- UniProtKB/TrEMBL
-
B7Z3G4
- Conserved Domains (3) summary
-
- cd11955
Location:732 → 784
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:487 → 674
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:26 → 289
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
-
NM_015326.5 → NP_056141.2 SLIT-ROBO Rho GTPase-activating protein 2 isoform a
See identical proteins and their annotated locations for NP_056141.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AB007925, AC244034, AC244035, AK294060, BC063527, DA110905
- Consensus CDS
-
CCDS73017.1
- UniProtKB/Swiss-Prot
- A2RUF3, O75044
- UniProtKB/TrEMBL
-
Q5VZB5
- Related
- ENSP00000459615.2, ENST00000573034.8
- Conserved Domains (4) summary
-
- cd07682
Location:26 → 289
- F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
- PHA03269
Location:963 → 1065
- PHA03269; envelope glycoprotein C; Provisional
- cd11955
Location:732 → 784
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:487 → 674
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
206203541..206464436
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011509354.3 → XP_011507656.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X1
- UniProtKB/TrEMBL
-
Q5VZB5
- Conserved Domains (4) summary
-
- cd07682
Location:26 → 289
- F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
- cd11955
Location:732 → 784
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:487 → 674
- RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
- pfam03867
Location:953 → 1077
- FTZ; Fushi tarazu (FTZ), N-terminal region
-
XM_011509355.3 → XP_011507657.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X2
- UniProtKB/TrEMBL
-
Q5VZB5
- Conserved Domains (4) summary
-
- cd07682
Location:26 → 288
- F-BAR_srGAP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2
- cd11955
Location:731 → 783
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:486 → 673
- RhoGAP_srGAP; RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs ...
- pfam03867
Location:952 → 1076
- FTZ; Fushi tarazu (FTZ), N-terminal region
-
XM_047416530.1 → XP_047272486.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X4
-
XM_047416531.1 → XP_047272487.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X5
-
XM_047416533.1 → XP_047272489.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X6
-
XM_024446014.2 → XP_024301782.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X3
- UniProtKB/TrEMBL
-
Q5VZB5
- Conserved Domains (4) summary
-
- cd11955
Location:701 → 753
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:456 → 643
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:1 → 258
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
- cl28111
Location:945 → 1047
- Marek_A; Marek's disease glycoprotein A
-
XM_024446015.2 → XP_024301783.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X3
- UniProtKB/TrEMBL
-
Q5VZB5
- Conserved Domains (4) summary
-
- cd11955
Location:701 → 753
- SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
- cd04383
Location:456 → 643
- RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
- cl12013
Location:1 → 258
- BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
- cl28111
Location:945 → 1047
- Marek_A; Marek's disease glycoprotein A
-
XM_047416534.1 → XP_047272490.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X7
-
XM_047416532.1 → XP_047272488.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X6
-
XM_047416535.1 → XP_047272491.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X8
-
XM_047416536.1 → XP_047272492.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X9
- Related
- ENSP00000397990.3, ENST00000419187.6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
205467727..205728612
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054335616.1 → XP_054191591.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X1
-
XM_054335617.1 → XP_054191592.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X2
-
XM_054335620.1 → XP_054191595.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X4
-
XM_054335621.1 → XP_054191596.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X5
-
XM_054335623.1 → XP_054191598.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X6
-
XM_054335618.1 → XP_054191593.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X3
-
XM_054335619.1 → XP_054191594.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X3
-
XM_054335625.1 → XP_054191600.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X7
-
XM_054335622.1 → XP_054191597.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X6
-
XM_054335626.1 → XP_054191601.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X8
-
XM_054335627.1 → XP_054191602.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X9
-
XM_054335624.1 → XP_054191599.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform X6
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001042758.1: Suppressed sequence
- Description
- NM_001042758.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.