DIA3 putative acid phosphatase DIA3 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Gene symbol: DIA3
Gene description: putative acid phosphatase DIA3
Primary source: FungiDB:YDL024C
Locus tag: YDL024C
See related: SGD:S000002182; AllianceGenome:SGD:S000002182; VEuPathDB:YDL024C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable acid phosphatase activity. Involved in invasive growth in response to glucose limitation and pseudohyphal growth. Located in fungal-type cell wall. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia and thyroid gland papillary carcinoma. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See DIA3 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 1

Sequence:: Chromosome: IV; NC_001136.10 (408451..409857, complement)

Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables acid phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acid phosphatase activity	IEA Inferred from Electronic Annotation more info
enables acid phosphatase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in invasive growth in response to glucose limitation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in pseudohyphal growth	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
is_active_in fungal-type cell wall	IBA Inferred from Biological aspect of Ancestor more info
located_in fungal-type cell wall	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: putative acid phosphatase DIA3

NP_010260.1

EC 3.1.3.2

hypothetical protein; involved in invasive and pseudohyphal growth

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001136.10 Reference assembly

Range

408451..409857 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001180083.1 → NP_010260.1 TPA: putative acid phosphatase DIA3 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_010260.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VRW7, P52290

UniProtKB/TrEMBL

A0A8H8UMQ1, B3LGS8, B5VFP1, C8Z4P5, N1PAA9

Conserved Domains (1) summary

pfam00328
Location:66 → 400

His_Phos_2; Histidine phosphatase superfamily (branch 2)