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    XKS1 xylulokinase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853108, updated on 18-Sep-2024

    Summary

    Official Symbol
    XKS1
    Official Full Name
    xylulokinase
    Primary source
    SGD:S000003426
    Locus tag
    YGR194C
    See related
    AllianceGenome:SGD:S000003426; FungiDB:YGR194C; VEuPathDB:YGR194C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables xylulokinase activity. Involved in xylulose catabolic process. Located in cytoplasm. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See XKS1 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (886073..887875, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 Neighboring gene Pdx1p Neighboring gene exosome non-catalytic core subunit SKI6 Neighboring gene Fyv8p

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables D-xylulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables D-xylulokinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables D-xylulokinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in D-xylose metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in carbohydrate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in xylulose catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in xylulose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    xylulokinase
    NP_011710.3
    • Xylulokinase; converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      886073..887875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181323.3NP_011710.3  TPA: xylulokinase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011710.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUX6, P42826
      UniProtKB/TrEMBL
      B3LI43, G3FCP2, N1P490
      Conserved Domains (1) summary
      cd07776
      Location:22545
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases