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    PTP4A3 protein tyrosine phosphatase 4A3 [ Homo sapiens (human) ]

    Gene ID: 11156, updated on 28-Oct-2024

    Summary

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    Official Symbol
    PTP4A3provided by HGNC
    Official Full Name
    protein tyrosine phosphatase 4A3provided by HGNC
    Primary source
    HGNC:HGNC:9636
    See related
    Ensembl:ENSG00000184489 MIM:606449; AllianceGenome:HGNC:9636
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRL3; PRL-3; PRL-R
    Summary
    This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
    Expression
    Broad expression in heart (RPKM 28.7), prostate (RPKM 11.1) and 20 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PTP4A3 in Genome Data Viewer
    Location:
    8q24.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (141392021..141432454)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (142513520..142559812)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (142402121..142442554)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142366583-142367204 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142367205-142367826 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142369677-142370273 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:142378149-142378698 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:142379063-142379245 Neighboring gene G protein-coupled receptor 20 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:142382601-142383224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:142383225-142383848 Neighboring gene uncharacterized LOC101928037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142385104-142385878 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142385879-142386654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:142386655-142387429 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142394223-142394840 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142401193-142401813 Neighboring gene antisense transcript of PTP4A3, liver carcinoma survival associated Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142413010-142413773 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:142417407-142417907 Neighboring gene VISTA enhancer hs1882 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:142441707-142442687 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:142443451-142444139 Neighboring gene Putative chemokine-related protein FP248 Neighboring gene uncharacterized LOC105375789 Neighboring gene small nucleolar RNA SNORD5 Neighboring gene maestro heat like repeat family member 5 (gene/pseudogene)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Expression of phosphatase of regenerating liver-3 (PRL-3) in endometrioid cancer and lymph nodes metastases. Guzińska-Ustymowicz K, et al. Adv Med Sci, 2013. PMID 23729584
    2. [Expression of phosphatase of regeneration liver-3 in human colorectal carcinoma and its prognosis value]. Zhao GP, et al. Zhonghua Wei Chang Wai Ke Za Zhi, 2008 Sep. PMID 18803057
    3. The expression of the phosphatase regenerating liver 3 gene is associated with outcome in patients with colorectal cancer. Tamagawa H, et al. Hepatogastroenterology, 2012 Oct. PMID 22440248
    4. Evaluation of PRL-3 expression, and its correlation with angiogenesis and invasion in hepatocellular carcinoma. Zhao WB, et al. Int J Mol Med, 2008 Aug. PMID 18636172
    5. The phosphatase of regenerating liver 3 (PRL-3) promotes cell migration through Arf-activity-dependent stimulation of integrin α5 recycling. Krndija D, et al. J Cell Sci, 2012 Aug 15. PMID 22595524

    See all (182) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Deubiquitinating Enzyme USP4 Functions as an Oncoprotein in Gastric Cancer and Mediates NF-kappaB Signaling by Regulating PRL-3 Expression.
      Title: The Deubiquitinating Enzyme USP4 Functions as an Oncoprotein in Gastric Cancer and Mediates NF-κB Signaling by Regulating PRL-3 Expression.
    2. The effects of endosulfan on cell migration and invasion in prostate cancer cells via the KCNQ1OT1/miR-137-3p/PTP4A3 axis.
      Title: The effects of endosulfan on cell migration and invasion in prostate cancer cells via the KCNQ1OT1/miR-137-3p/PTP4A3 axis.
    3. The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with beta3 -tubulin.
      Title: The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 -tubulin.
    4. The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition.
      Title: The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition.
    5. PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.
      Title: PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.
    6. Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression.
      Title: Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression.
    7. PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2.
      Title: PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2.
    8. Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer.
      Title: Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer.
    9. Phosphatase of regenerating liver-3 regulates cancer cell metabolism in multiple myeloma.
      Title: Phosphatase of regenerating liver-3 regulates cancer cell metabolism in multiple myeloma.
    10. PRL-3 facilitates Hepatocellular Carcinoma progression by co-amplifying with and activating FAK.
      Title: PRL-3 facilitates Hepatocellular Carcinoma progression by co-amplifying with and activating FAK.
    Submit: New GeneRIF Correction See all GeneRIFs (159)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to leukemia inhibitory factor IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endothelial cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within endothelial cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of establishment of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of non-canonical NF-kappaB signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of vascular permeability IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of vascular endothelial growth factor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein tyrosine phosphatase type IVA 3
    Names
    phosphatase of regenerating liver 3
    potentially prenylated protein tyrosine phosphatase
    protein tyrosine phosphatase type IVA, member 3
    protein-tyrosine phosphatase of regenerating liver 3
    NP_009010.2
    NP_116000.1
    XP_005250821.1
    XP_006716563.1
    XP_011515105.1
    XP_011515107.1
    XP_016868487.1
    XP_016868488.1
    XP_024302825.1
    XP_047277243.1
    XP_047277244.1
    XP_047277245.1
    XP_047277246.1
    XP_047277247.1
    XP_047277248.1
    XP_047277249.1
    XP_047277250.1
    XP_047277251.1
    XP_047277252.1
    XP_047277253.1
    XP_047277254.1
    XP_047277255.1
    XP_047277256.1
    XP_047277257.1
    XP_047277258.1
    XP_047277259.1
    XP_047277260.1
    XP_047277261.1
    XP_047277262.1
    XP_054184761.1
    XP_054184762.1
    XP_054184763.1
    XP_054184764.1
    XP_054184765.1
    XP_054184766.1
    XP_054184767.1
    XP_054184768.1
    XP_054184769.1
    XP_054184770.1
    XP_054184771.1
    XP_054184772.1
    XP_054184773.1
    XP_054184774.1
    XP_054184775.1
    XP_054184776.1
    XP_054184777.1
    XP_054184778.1
    XP_054184779.1
    XP_054184780.1
    XP_054184781.1
    XP_054184782.1
    XP_054184783.1
    XP_054184784.1
    XP_054184785.1
    XP_054184786.1
    XP_054184787.1
    XP_054184788.1
    XP_054184789.1
    XP_054184790.1
    XP_054184791.1
    XP_054184792.1
    XP_054184793.1
    XP_054184794.1
    XP_054184795.1
    XP_054184796.1
    XP_054189029.1
    XP_054189030.1
    XP_054189031.1
    XP_054189032.1
    XP_054189033.1
    XP_054189034.1
    XP_054189035.1
    XP_054189036.1
    XP_054189037.1
    XP_054189038.1
    XP_054189039.1
    XP_054189040.1
    XP_054189041.1
    XP_054189042.1
    XP_054189043.1
    XP_054189044.1
    XP_054189045.1
    XP_054189046.1
    XP_054189047.1
    XP_054189048.1
    XP_054189049.1
    XP_054189050.1
    XP_054189051.1
    XP_054189052.1
    XP_054189053.1
    XP_054189054.1
    XP_054189055.1
    XP_054189056.1
    XP_054215616.1
    XP_054215617.1
    XP_054215618.1
    XP_054215619.1
    XP_054215620.1
    XP_054215621.1
    XP_054215622.1
    XP_054215623.1
    XP_054215624.1
    XP_054215625.1
    XP_054215626.1
    XP_054215627.1
    XP_054215628.1
    XP_054215629.1
    XP_054215630.1
    XP_054215631.1
    XP_054215632.1
    XP_054215633.1
    XP_054215634.1
    XP_054215635.1
    XP_054215636.1
    XP_054215637.1
    XP_054215638.1
    XP_054215639.1
    XP_054215640.1
    XP_054215641.1
    XP_054215642.1
    XP_054215643.1
    XP_054215644.1
    XP_054215645.1
    XP_054215646.1
    XP_054215647.1
    XP_054215648.1
    XP_054215649.1
    XP_054215650.1
    XP_054215651.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007079.3 → NP_009010.2  protein tyrosine phosphatase type IVA 3 isoform 2

      See identical proteins and their annotated locations for NP_009010.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AC100803, AK311257, BC003105
      Consensus CDS
      CCDS6382.1
      UniProtKB/Swiss-Prot
      O75365
      Conserved Domains (1) summary
      cl28904
      Location:5 → 133
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    2. NM_032611.3 → NP_116000.1  protein tyrosine phosphatase type IVA 3 isoform 1

      See identical proteins and their annotated locations for NP_116000.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC100803, AK311257, BC003105, BQ637038
      Consensus CDS
      CCDS6383.1
      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Related
      ENSP00000428976.1, ENST00000521578.6
      Conserved Domains (1) summary
      cd18535
      Location:5 → 158
      PTP-IVa3; protein tyrosine phosphatase type IVA 3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      141392021..141432454
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017012998.3 → XP_016868487.1  protein tyrosine phosphatase type IVA 3 isoform X3

      UniProtKB/Swiss-Prot
      O75365
      Related
      ENSP00000428758.1, ENST00000520105.5
      Conserved Domains (1) summary
      cl28904
      Location:5 → 133
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    2. XM_006716500.4 → XP_006716563.1  protein tyrosine phosphatase type IVA 3 isoform X2

      See identical proteins and their annotated locations for XP_006716563.1

      Conserved Domains (1) summary
      cl28904
      Location:10 → 134
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    3. XM_017012999.3 → XP_016868488.1  protein tyrosine phosphatase type IVA 3 isoform X4

    4. XM_011516805.2 → XP_011515107.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_011515107.1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Conserved Domains (1) summary
      cd18535
      Location:5 → 158
      PTP-IVa3; protein tyrosine phosphatase type IVA 3

    5. XM_011516803.2 → XP_011515105.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_011515105.1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Related
      ENSP00000332274.1, ENST00000329397.6
      Conserved Domains (1) summary
      cd18535
      Location:5 → 158
      PTP-IVa3; protein tyrosine phosphatase type IVA 3

    6. XM_047421300.1 → XP_047277256.1  protein tyrosine phosphatase type IVA 3 isoform X3

    7. XM_047421296.1 → XP_047277252.1  protein tyrosine phosphatase type IVA 3 isoform X2

    8. XM_047421290.1 → XP_047277246.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    9. XM_047421305.1 → XP_047277261.1  protein tyrosine phosphatase type IVA 3 isoform X3

    10. XM_047421298.1 → XP_047277254.1  protein tyrosine phosphatase type IVA 3 isoform X3

    11. XM_047421288.1 → XP_047277244.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Related
      ENSP00000505068.1, ENST00000680615.1

    12. XM_047421301.1 → XP_047277257.1  protein tyrosine phosphatase type IVA 3 isoform X3

    13. XM_047421297.1 → XP_047277253.1  protein tyrosine phosphatase type IVA 3 isoform X2

    14. XM_047421291.1 → XP_047277247.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Related
      ENSP00000331730.2, ENST00000349124.3

    15. XM_047421304.1 → XP_047277260.1  protein tyrosine phosphatase type IVA 3 isoform X3

    16. XM_005250764.3 → XP_005250821.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_005250821.1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Conserved Domains (1) summary
      cd18535
      Location:5 → 158
      PTP-IVa3; protein tyrosine phosphatase type IVA 3

    17. XM_047421303.1 → XP_047277259.1  protein tyrosine phosphatase type IVA 3 isoform X3

    18. XM_047421292.1 → XP_047277248.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    19. XM_047421294.1 → XP_047277250.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    20. XM_047421289.1 → XP_047277245.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    21. XM_047421302.1 → XP_047277258.1  protein tyrosine phosphatase type IVA 3 isoform X3

      Related
      ENSP00000506615.1, ENST00000681443.1

    22. XM_047421287.1 → XP_047277243.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    23. XM_047421293.1 → XP_047277249.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    24. XM_024447057.2 → XP_024302825.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5
      Conserved Domains (1) summary
      cd18535
      Location:5 → 158
      PTP-IVa3; protein tyrosine phosphatase type IVA 3

    25. XM_047421299.1 → XP_047277255.1  protein tyrosine phosphatase type IVA 3 isoform X3

    26. XM_047421295.1 → XP_047277251.1  protein tyrosine phosphatase type IVA 3 isoform X2

    27. XM_047421306.1 → XP_047277262.1  protein tyrosine phosphatase type IVA 3 isoform X4

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791786.1 Reference GRCh38.p14 PATCHES

      Range
      58575..99008
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054333070.1 → XP_054189045.1  protein tyrosine phosphatase type IVA 3 isoform X3

    2. XM_054333065.1 → XP_054189040.1  protein tyrosine phosphatase type IVA 3 isoform X2

    3. XM_054333080.1 → XP_054189055.1  protein tyrosine phosphatase type IVA 3 isoform X4

    4. XM_054333061.1 → XP_054189036.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    5. XM_054333055.1 → XP_054189030.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    6. XM_054333072.1 → XP_054189047.1  protein tyrosine phosphatase type IVA 3 isoform X3

    7. XM_054333066.1 → XP_054189041.1  protein tyrosine phosphatase type IVA 3 isoform X2

    8. XM_054333058.1 → XP_054189033.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    9. XM_054333076.1 → XP_054189051.1  protein tyrosine phosphatase type IVA 3 isoform X3

    10. XM_054333056.1 → XP_054189031.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    11. XM_054333060.1 → XP_054189035.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    12. XM_054333057.1 → XP_054189032.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    13. XM_054333074.1 → XP_054189049.1  protein tyrosine phosphatase type IVA 3 isoform X3

    14. XM_054333054.1 → XP_054189029.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    15. XM_054333071.1 → XP_054189046.1  protein tyrosine phosphatase type IVA 3 isoform X3

    16. XM_054333073.1 → XP_054189048.1  protein tyrosine phosphatase type IVA 3 isoform X3

    17. XM_054333068.1 → XP_054189043.1  protein tyrosine phosphatase type IVA 3 isoform X2

    18. XM_054333075.1 → XP_054189050.1  protein tyrosine phosphatase type IVA 3 isoform X3

    19. XM_054333067.1 → XP_054189042.1  protein tyrosine phosphatase type IVA 3 isoform X2

    20. XM_054333062.1 → XP_054189037.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    21. XM_054333064.1 → XP_054189039.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    22. XM_054333078.1 → XP_054189053.1  protein tyrosine phosphatase type IVA 3 isoform X3

    23. XM_054333077.1 → XP_054189052.1  protein tyrosine phosphatase type IVA 3 isoform X3

    24. XM_054333069.1 → XP_054189044.1  protein tyrosine phosphatase type IVA 3 isoform X2

    25. XM_054333081.1 → XP_054189056.1  protein tyrosine phosphatase type IVA 3 isoform X4

    26. XM_054333063.1 → XP_054189038.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    27. XM_054333059.1 → XP_054189034.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    28. XM_054333079.1 → XP_054189054.1  protein tyrosine phosphatase type IVA 3 isoform X4

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187574.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      58573..104910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054328810.1 → XP_054184785.1  protein tyrosine phosphatase type IVA 3 isoform X3

    2. XM_054328802.1 → XP_054184777.1  protein tyrosine phosphatase type IVA 3 isoform X2

    3. XM_054328819.1 → XP_054184794.1  protein tyrosine phosphatase type IVA 3 isoform X4

    4. XM_054328798.1 → XP_054184773.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    5. XM_054328792.1 → XP_054184767.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    6. XM_054328814.1 → XP_054184789.1  protein tyrosine phosphatase type IVA 3 isoform X3

    7. XM_054328807.1 → XP_054184782.1  protein tyrosine phosphatase type IVA 3 isoform X2

    8. XM_054328817.1 → XP_054184792.1  protein tyrosine phosphatase type IVA 3 isoform X3

    9. XM_054328793.1 → XP_054184768.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    10. XM_054328799.1 → XP_054184774.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    11. XM_054328820.1 → XP_054184795.1  protein tyrosine phosphatase type IVA 3 isoform X4

    12. XM_054328809.1 → XP_054184784.1  protein tyrosine phosphatase type IVA 3 isoform X3

    13. XM_054328803.1 → XP_054184778.1  protein tyrosine phosphatase type IVA 3 isoform X2

    14. XM_054328794.1 → XP_054184769.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    15. XM_054328789.1 → XP_054184764.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    16. XM_054328795.1 → XP_054184770.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    17. XM_054328791.1 → XP_054184766.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    18. XM_054328815.1 → XP_054184790.1  protein tyrosine phosphatase type IVA 3 isoform X3

    19. XM_054328788.1 → XP_054184763.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    20. XM_054328811.1 → XP_054184786.1  protein tyrosine phosphatase type IVA 3 isoform X3

    21. XM_054328813.1 → XP_054184788.1  protein tyrosine phosphatase type IVA 3 isoform X3

    22. XM_054328805.1 → XP_054184780.1  protein tyrosine phosphatase type IVA 3 isoform X2

    23. XM_054328816.1 → XP_054184791.1  protein tyrosine phosphatase type IVA 3 isoform X3

    24. XM_054328804.1 → XP_054184779.1  protein tyrosine phosphatase type IVA 3 isoform X2

    25. XM_054328808.1 → XP_054184783.1  protein tyrosine phosphatase type IVA 3 isoform X3

    26. XM_054328801.1 → XP_054184776.1  protein tyrosine phosphatase type IVA 3 isoform X2

    27. XM_054328818.1 → XP_054184793.1  protein tyrosine phosphatase type IVA 3 isoform X4

    28. XM_054328796.1 → XP_054184771.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    29. XM_054328812.1 → XP_054184787.1  protein tyrosine phosphatase type IVA 3 isoform X3

    30. XM_054328787.1 → XP_054184762.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    31. XM_054328806.1 → XP_054184781.1  protein tyrosine phosphatase type IVA 3 isoform X2

    32. XM_054328790.1 → XP_054184765.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    33. XM_054328786.1 → XP_054184761.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    34. XM_054328797.1 → XP_054184772.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    35. XM_054328800.1 → XP_054184775.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    36. XM_054328821.1 → XP_054184796.1  protein tyrosine phosphatase type IVA 3 isoform X4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      142513520..142559812
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054359665.1 → XP_054215640.1  protein tyrosine phosphatase type IVA 3 isoform X3

    2. XM_054359657.1 → XP_054215632.1  protein tyrosine phosphatase type IVA 3 isoform X2

    3. XM_054359674.1 → XP_054215649.1  protein tyrosine phosphatase type IVA 3 isoform X4

    4. XM_054359653.1 → XP_054215628.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    5. XM_054359644.1 → XP_054215619.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    6. XM_054359668.1 → XP_054215643.1  protein tyrosine phosphatase type IVA 3 isoform X3

    7. XM_054359659.1 → XP_054215634.1  protein tyrosine phosphatase type IVA 3 isoform X2

    8. XM_054359672.1 → XP_054215647.1  protein tyrosine phosphatase type IVA 3 isoform X3

    9. XM_054359648.1 → XP_054215623.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    10. XM_054359654.1 → XP_054215629.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    11. XM_054359675.1 → XP_054215650.1  protein tyrosine phosphatase type IVA 3 isoform X4

    12. XM_054359664.1 → XP_054215639.1  protein tyrosine phosphatase type IVA 3 isoform X3

    13. XM_054359658.1 → XP_054215633.1  protein tyrosine phosphatase type IVA 3 isoform X2

    14. XM_054359649.1 → XP_054215624.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    15. XM_054359645.1 → XP_054215620.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    16. XM_054359650.1 → XP_054215625.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    17. XM_054359647.1 → XP_054215622.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    18. XM_054359670.1 → XP_054215645.1  protein tyrosine phosphatase type IVA 3 isoform X3

    19. XM_054359643.1 → XP_054215618.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    20. XM_054359666.1 → XP_054215641.1  protein tyrosine phosphatase type IVA 3 isoform X3

    21. XM_054359669.1 → XP_054215644.1  protein tyrosine phosphatase type IVA 3 isoform X3

    22. XM_054359661.1 → XP_054215636.1  protein tyrosine phosphatase type IVA 3 isoform X2

    23. XM_054359671.1 → XP_054215646.1  protein tyrosine phosphatase type IVA 3 isoform X3

    24. XM_054359660.1 → XP_054215635.1  protein tyrosine phosphatase type IVA 3 isoform X2

    25. XM_054359663.1 → XP_054215638.1  protein tyrosine phosphatase type IVA 3 isoform X3

    26. XM_054359656.1 → XP_054215631.1  protein tyrosine phosphatase type IVA 3 isoform X2

    27. XM_054359673.1 → XP_054215648.1  protein tyrosine phosphatase type IVA 3 isoform X4

    28. XM_054359651.1 → XP_054215626.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    29. XM_054359667.1 → XP_054215642.1  protein tyrosine phosphatase type IVA 3 isoform X3

    30. XM_054359642.1 → XP_054215617.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    31. XM_054359662.1 → XP_054215637.1  protein tyrosine phosphatase type IVA 3 isoform X2

    32. XM_054359646.1 → XP_054215621.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    33. XM_054359641.1 → XP_054215616.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    34. XM_054359652.1 → XP_054215627.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    35. XM_054359655.1 → XP_054215630.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      O75365, Q8IVN5, Q99849, Q9BTW5

    36. XM_054359676.1 → XP_054215651.1  protein tyrosine phosphatase type IVA 3 isoform X4

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O75365.2 GenPept UniProtKB/Swiss-Prot:O75365

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