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    BDNF-AS BDNF antisense RNA [ Homo sapiens (human) ]

    Gene ID: 497258, updated on 17-Sep-2024

    Summary

    Official Symbol
    BDNF-ASprovided by HGNC
    Official Full Name
    BDNF antisense RNAprovided by HGNC
    Primary source
    HGNC:HGNC:20608
    See related
    Ensembl:ENSG00000245573 MIM:611468; AllianceGenome:HGNC:20608
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BDNF; BDNFAS; BDNFOS; BDNF-AS1; ANTI-BDNF; NCRNA00049
    Expression
    Ubiquitous expression in brain (RPKM 3.5), thyroid (RPKM 1.9) and 23 other tissues See more
    NEW
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    Try the new Transcript table

    Genomic context

    See BDNF-AS in Genome Data Viewer
    Location:
    11p14.1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (27506852..27698171)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (27647322..27838600)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27528399..27719718)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37a pseudogene 7 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:27527877-27529076 Neighboring gene lin-7 homolog C, crumbs cell polarity complex component Neighboring gene RNA, 5S ribosomal pseudogene 339 Neighboring gene microRNA 8087 Neighboring gene ribosomal protein S25 pseudogene 1 Neighboring gene Sharpr-MPRA regulatory region 104 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:27650686-27651472 Neighboring gene long intergenic non-protein coding RNA 678 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:27653431-27654320 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:27655211-27656100 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:27656101-27656990 Neighboring gene Sharpr-MPRA regulatory region 8127 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:27708921-27709828 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:27709829-27710734 Neighboring gene brain derived neurotrophic factor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:27743527-27744035 Neighboring gene uncharacterized LOC124902652 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:27762065-27762756 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:27817576-27818442 Neighboring gene CBX3 pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome wide association study identifies KCNMA1 contributing to human obesity.
    EBI GWAS Catalog
    Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
    EBI GWAS Catalog
    Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
    EBI GWAS Catalog
    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • BDNF antisense RNA (non-protein coding)
    • BDNF antisense RNA 1 (non-protein coding)
    • BDNF opposite strand (non-protein coding)
    • brain-derived neurotrophic factor opposite strand

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002832.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (BT2B) represents the longest transcript.
      Source sequence(s)
      AC100771, AC104563, KF459669
      Related
      ENST00000499008.8
    2. NR_033312.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (BT1C) lacks an alternate exon and uses an alternate 3' splice pattern, compared to variant BT2B.
      Source sequence(s)
      AC100771, AC104563, KF459669
      Related
      ENST00000499568.3
    3. NR_033313.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (BT1A) lacks an alternate exon and uses an alternate 3' splice pattern, compared to variant BT2B.
      Source sequence(s)
      AC100771, AC104563, KF459669
      Related
      ENST00000502161.7
    4. NR_033314.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (BT2A) lacks an alternate exon, compared to variant BT2B.
      Source sequence(s)
      AC100771, AC104563, KF459669
      Related
      ENST00000651193.1
    5. NR_033315.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (BT1B) lacks two alternate exons and uses an alternate 3' splice pattern, compared to variant BT2B.
      Source sequence(s)
      AC100771, AC104563, KF459669
      Related
      ENST00000500662.7

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      27506852..27698171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      27647322..27838600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)