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    Gspt2 G1 to S phase transition 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501582, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Gspt2provided by RGD
    Official Full Name
    G1 to S phase transition 2provided by RGD
    Primary source
    RGD:1563213
    See related
    Ensembl:ENSRNOG00000048817 AllianceGenome:RGD:1563213
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563213
    Summary
    Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in cytoplasmic translational termination. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Orthologous to human GSPT2 (G1 to S phase transition 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Gspt2 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (63582649..63597467)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (59587237..59589758)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (63959131..63961652, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene queuine tRNA-ribosyltransferase accessory subunit 2, pseudogene 1 Neighboring gene zinc finger, X-linked, duplicated B Neighboring gene zinc finger, X-linked, duplicated A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables translation release factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation release factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational termination ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of translation release factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    eukaryotic peptide chain release factor GTP-binding subunit ERF3B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109319.1 → NP_001102789.1  eukaryotic peptide chain release factor GTP-binding subunit ERF3B

      See identical proteins and their annotated locations for NP_001102789.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473966
      UniProtKB/TrEMBL
      A0A096MJE3, A6IQ16
      Related
      ENSRNOP00000068098.1, ENSRNOT00000071762.3
      Conserved Domains (5) summary
      cd01883
      Location:209 → 425
      EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
      COG5256
      Location:205 → 629
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      pfam07145
      Location:54 → 71
      PAM2; Ataxin-2 C-terminal region
      cd04089
      Location:434 → 514
      eRF3_II; Domain II of the eukaryotic class II release factor
      cd03704
      Location:521 → 627
      eRF3_C_III; C-terminal domain of eRF3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      63582649..63597467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280251.1 → XP_063136321.1  eukaryotic peptide chain release factor GTP-binding subunit ERF3B isoform X1

      UniProtKB/TrEMBL
      A0A096MJE3, A6IQ16

    2. XM_063280252.1 → XP_063136322.1  eukaryotic peptide chain release factor GTP-binding subunit ERF3B isoform X1

      UniProtKB/TrEMBL
      A0A096MJE3, A6IQ16

    3. XM_063280250.1 → XP_063136320.1  eukaryotic peptide chain release factor GTP-binding subunit ERF3B isoform X1

      UniProtKB/TrEMBL
      A0A096MJE3, A6IQ16
    Nucleotide Protein Strain
    Heading Accession and Version

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