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    Ccdc149 coiled-coil domain containing 149 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688939, updated on 10-Oct-2024

    Summary

    Official Symbol
    Ccdc149provided by RGD
    Official Full Name
    coiled-coil domain containing 149provided by RGD
    Primary source
    RGD:1582968
    See related
    EnsemblRapid:ENSRNOG00000024454 AllianceGenome:RGD:1582968
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human CCDC149 (coiled-coil domain containing 149). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 60.2), Heart (RPKM 47.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ccdc149 in Genome Data Viewer
    Location:
    14q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (62722567..62817778)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (58509583..58605017)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (60857924..60953504)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481905 Neighboring gene uncharacterized LOC134481755 Neighboring gene superoxide dismutase 3 Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    coiled-coil domain containing 149; coiled-coil domain-containing protein 149

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432958.1NP_001419887.1  coiled-coil domain containing 149 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      F1LVF5
    2. NM_001432959.1NP_001419888.1  coiled-coil domain containing 149 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I6GFS3
    3. NM_001432960.1NP_001419889.1  coiled-coil domain containing 149 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
    4. NM_001432961.1NP_001419890.1  coiled-coil domain containing 149 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      62722567..62817778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251034.5XP_006251096.1  coiled-coil domain-containing protein 149 isoform X2

      Related
      ENSRNOP00000094579.2, ENSRNOT00000097645.2
      Conserved Domains (2) summary
      pfam09789
      Location:21333
      DUF2353; Uncharacterized coiled-coil protein (DUF2353)
      cl00459
      Location:86206
      MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily
    2. XM_039092757.2XP_038948685.1  coiled-coil domain-containing protein 149 isoform X1

      Related
      ENSRNOP00000029437.4, ENSRNOT00000034411.6
      Conserved Domains (1) summary
      pfam09789
      Location:21333
      DUF2353; Uncharacterized coiled-coil protein (DUF2353)
    3. XM_063273760.1XP_063129830.1  coiled-coil domain-containing protein 149 isoform X3

      Related
      ENSRNOP00000088058.2, ENSRNOT00000118912.2
    4. XM_063273761.1XP_063129831.1  coiled-coil domain-containing protein 149 isoform X4