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    Zfp282 zinc finger protein 282 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297065, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Zfp282provided by RGD
    Official Full Name
    zinc finger protein 282provided by RGD
    Primary source
    RGD:1306278
    See related
    EnsemblRapid:ENSRNOG00000026981 AllianceGenome:RGD:1306278
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf282
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Orthologous to human ZNF282 (zinc finger protein 282). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 69.8), Lung (RPKM 63.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp282 in Genome Data Viewer
    Location:
    4q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (78215940..78241193)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (76884996..76910250)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (77554269..77580714)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 786 Neighboring gene uncharacterized LOC134486577 Neighboring gene zinc finger protein 398 Neighboring gene Zinc finger protein 212 Neighboring gene ATP synthase subunit delta, mitochondrial pseudogene Neighboring gene zinc finger protein 956 Neighboring gene zinc finger protein 783

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 282

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106592.2 → NP_001100062.1  zinc finger protein 282

      See identical proteins and their annotated locations for NP_001100062.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6K0D4, A6K0D5, D4A4V7
      Related
      ENSRNOP00000030771.4, ENSRNOT00000037248.7
      Conserved Domains (6) summary
      smart00349
      Location:198 → 260
      KRAB; krueppel associated box
      COG5048
      Location:568 → 621
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:544 → 564
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:570 → 592
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:198 → 237
      KRAB; KRAB box
      pfam13465
      Location:612 → 637
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      78215940..78241193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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