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    Plekha6 pleckstrin homology domain containing A6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360842, updated on 17-Aug-2024

    Summary

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    Symbol
    Plekha6provided by RGD
    Full Name
    pleckstrin homology domain containing A6provided by RGD
    Primary source
    RGD:1564395
    See related
    EnsemblRapid:ENSRNOG00000002907 AllianceGenome:RGD:1564395
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564395
    Summary
    Orthologous to human PLEKHA6 (pleckstrin homology domain containing A6). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 97.1), Adrenal (RPKM 44.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    13q13
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (47166899..47307003)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (44614740..44754951)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (50555454..50582236, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene MDM4 regulator of p53 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Neighboring gene protein phosphatase 1, regulatory subunit 15B Neighboring gene golgi transport 1A Neighboring gene KiSS-1 metastasis-suppressor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Congenic mapping and sequence analysis of the Renin locus. Flister MJ, et al. Hypertension, 2013 Apr. PMID 23460292, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    pleckstrin homology domain-containing family A member 6
    Names
    pleckstrin homology domain containing, family A member 6
    pleckstrin homology domain-containing family A member 6-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427839.1 → NP_001414768.1  pleckstrin homology domain-containing family A member 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A0A8I6AI30
      Related
      ENSRNOP00000093717.2, ENSRNOT00000107878.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      47166899..47307003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091292.2 → XP_038947220.2  pleckstrin homology domain-containing family A member 6 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AI30

    2. XM_039091296.2 → XP_038947224.2  pleckstrin homology domain-containing family A member 6 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AI30

    3. XM_039091307.2 → XP_038947235.2  pleckstrin homology domain-containing family A member 6 isoform X23

      UniProtKB/TrEMBL
      A0A8I6AI30

    4. XM_039091295.2 → XP_038947223.1  pleckstrin homology domain-containing family A member 6 isoform X7

      UniProtKB/TrEMBL
      A0A8I6AI30
      Conserved Domains (3) summary
      PRK14086
      Location:370 → 531
      dnaA; chromosomal replication initiator protein DnaA
      cd13248
      Location:165 → 288
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      TIGR04523
      Location:723 → 869
      Mplasa_alph_rch; helix-rich Mycoplasma protein

    5. XM_063272453.1 → XP_063128523.1  pleckstrin homology domain-containing family A member 6 isoform X21

      UniProtKB/TrEMBL
      A0A8I6AI30

    6. XM_063272444.1 → XP_063128514.1  pleckstrin homology domain-containing family A member 6 isoform X10

      UniProtKB/TrEMBL
      A0A8I6AI30

    7. XM_063272462.1 → XP_063128532.1  pleckstrin homology domain-containing family A member 6 isoform X30

      UniProtKB/TrEMBL
      A6IC71

    8. XM_063272463.1 → XP_063128533.1  pleckstrin homology domain-containing family A member 6 isoform X31

      UniProtKB/TrEMBL
      A0A8I6AC02

    9. XM_063272440.1 → XP_063128510.1  pleckstrin homology domain-containing family A member 6 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AI30

    10. XM_063272449.1 → XP_063128519.1  pleckstrin homology domain-containing family A member 6 isoform X17

      UniProtKB/TrEMBL
      A0A8I6AI30

    11. XM_063272457.1 → XP_063128527.1  pleckstrin homology domain-containing family A member 6 isoform X25

      UniProtKB/TrEMBL
      A6IC71

    12. XM_039091294.2 → XP_038947222.1  pleckstrin homology domain-containing family A member 6 isoform X6

      UniProtKB/TrEMBL
      A0A8I6AI30
      Conserved Domains (3) summary
      PRK14086
      Location:350 → 511
      dnaA; chromosomal replication initiator protein DnaA
      cd13248
      Location:165 → 268
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      TIGR04523
      Location:703 → 849
      Mplasa_alph_rch; helix-rich Mycoplasma protein

    13. XM_063272461.1 → XP_063128531.1  pleckstrin homology domain-containing family A member 6 isoform X29

      UniProtKB/TrEMBL
      A0A8I6AC02
      Related
      ENSRNOP00000093888.1, ENSRNOT00000100205.2

    14. XM_063272439.1 → XP_063128509.1  pleckstrin homology domain-containing family A member 6 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AI30

    15. XM_063272447.1 → XP_063128517.1  pleckstrin homology domain-containing family A member 6 isoform X13

      UniProtKB/TrEMBL
      A0A8I6AI30

    16. XM_063272443.1 → XP_063128513.1  pleckstrin homology domain-containing family A member 6 isoform X9

      UniProtKB/TrEMBL
      A0A8I6AI30

    17. XM_063272452.1 → XP_063128522.1  pleckstrin homology domain-containing family A member 6 isoform X20

      UniProtKB/TrEMBL
      A6IC71

    18. XM_063272441.1 → XP_063128511.1  pleckstrin homology domain-containing family A member 6 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AI30

    19. XM_063272445.1 → XP_063128515.1  pleckstrin homology domain-containing family A member 6 isoform X11

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    20. XM_039091302.2 → XP_038947230.2  pleckstrin homology domain-containing family A member 6 isoform X15

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    21. XM_063272446.1 → XP_063128516.1  pleckstrin homology domain-containing family A member 6 isoform X12

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    22. XM_063272450.1 → XP_063128520.1  pleckstrin homology domain-containing family A member 6 isoform X18

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    23. XM_063272455.1 → XP_063128525.1  pleckstrin homology domain-containing family A member 6 isoform X24

      UniProtKB/TrEMBL
      A6IC71

    24. XM_039091306.2 → XP_038947234.2  pleckstrin homology domain-containing family A member 6 isoform X22

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    25. XM_063272460.1 → XP_063128530.1  pleckstrin homology domain-containing family A member 6 isoform X28

      UniProtKB/TrEMBL
      A0A8I6AC02

    26. XM_063272442.1 → XP_063128512.1  pleckstrin homology domain-containing family A member 6 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AI30

    27. XM_063272448.1 → XP_063128518.1  pleckstrin homology domain-containing family A member 6 isoform X14

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    28. XM_063272451.1 → XP_063128521.1  pleckstrin homology domain-containing family A member 6 isoform X19

      UniProtKB/TrEMBL
      A0A8I6AI30

    29. XM_039091308.2 → XP_038947236.2  pleckstrin homology domain-containing family A member 6 isoform X23

      UniProtKB/TrEMBL
      A0A8I6AI30

    30. XM_063272458.1 → XP_063128528.1  pleckstrin homology domain-containing family A member 6 isoform X26

      UniProtKB/TrEMBL
      A0A8I6AI30

    31. XM_063272454.1 → XP_063128524.1  pleckstrin homology domain-containing family A member 6 isoform X23

      UniProtKB/TrEMBL
      A0A8I6AI30

    32. XM_039091309.2 → XP_038947237.2  pleckstrin homology domain-containing family A member 6 isoform X23

      UniProtKB/TrEMBL
      A0A8I6AI30

    33. XM_039091303.2 → XP_038947231.2  pleckstrin homology domain-containing family A member 6 isoform X16

      UniProtKB/TrEMBL
      A0A8I6AI30

    34. XM_063272459.1 → XP_063128529.1  pleckstrin homology domain-containing family A member 6 isoform X27

      UniProtKB/TrEMBL
      A0A8I5ZUH5

    35. XM_341118.10 → XP_341119.7  pleckstrin homology domain-containing family A member 6 isoform X32

      UniProtKB/TrEMBL
      A0A8I6AI30
    Nucleotide Protein Strain
    Heading Accession and Version

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