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    Atp6ap1l ATPase H+ transporting accessory protein 1 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361875, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Atp6ap1lprovided by RGD
    Official Full Name
    ATPase H+ transporting accessory protein 1 likeprovided by RGD
    Primary source
    RGD:1564936
    See related
    EnsemblRapid:ENSRNOG00000040201 AllianceGenome:RGD:1564936
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564936
    Summary
    Predicted to be involved in regulation of cellular pH. Predicted to be integral component of membrane. Predicted to be part of plasma membrane proton-transporting V-type ATPase complex. Orthologous to human ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 105.2), Testes (RPKM 80.6) and 4 other tissues See more
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    Genomic context

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    See Atp6ap1l in Genome Data Viewer
    Location:
    2q12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (23772724..23814913, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22037542..22079376, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (19781375..19809355, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U109 Neighboring gene transmembrane protein 167A Neighboring gene uncharacterized LOC134485712 Neighboring gene ribosomal protein S23 Neighboring gene autophagy related 10 Neighboring gene uncharacterized LOC120100664 Neighboring gene uncharacterized LOC134485814

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of cellular pH IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    V-type proton ATPase subunit S1-like protein
    Names
    ATPase, H+ transporting, lysosomal accessory protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191843.1 → NP_001178772.1  V-type proton ATPase subunit S1-like protein precursor

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      D3ZA00
      Related
      ENSRNOP00000050073.4, ENSRNOT00000044237.6
      Conserved Domains (1) summary
      pfam05827
      Location:153 → 293
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      23772724..23814913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102521.2 → XP_038958449.1  V-type proton ATPase subunit S1-like protein isoform X3

      Related
      ENSRNOP00000111706.1, ENSRNOT00000146394.1
      Conserved Domains (1) summary
      pfam05827
      Location:159 → 299
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    2. XM_039102515.2 → XP_038958443.1  V-type proton ATPase subunit S1-like protein isoform X1

      Related
      ENSRNOP00000103211.1, ENSRNOT00000127775.1
      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    3. XM_039102518.1 → XP_038958446.1  V-type proton ATPase subunit S1-like protein isoform X1

      Related
      ENSRNOP00000108078.1, ENSRNOT00000144554.1
      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    4. XM_039102512.2 → XP_038958440.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    5. XM_063282000.1 → XP_063138070.1  V-type proton ATPase subunit S1-like protein isoform X1

    6. XM_063282001.1 → XP_063138071.1  V-type proton ATPase subunit S1-like protein isoform X2

    7. XM_039102516.2 → XP_038958444.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    8. XM_039102513.2 → XP_038958441.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    9. XM_039102517.2 → XP_038958445.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    10. XM_039102510.2 → XP_038958438.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    11. XM_063281999.1 → XP_063138069.1  V-type proton ATPase subunit S1-like protein isoform X1

    12. XM_039102511.2 → XP_038958439.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    13. XM_039102522.2 → XP_038958450.1  V-type proton ATPase subunit S1-like protein isoform X4

      UniProtKB/TrEMBL
      D3ZA00
      Conserved Domains (1) summary
      pfam05827
      Location:153 → 293
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    14. XM_039102520.2 → XP_038958448.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

    15. XM_039102514.2 → XP_038958442.1  V-type proton ATPase subunit S1-like protein isoform X1

      Conserved Domains (1) summary
      pfam05827
      Location:161 → 301
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
    Nucleotide Protein Strain
    Heading Accession and Version

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