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    Sdad1 SDA1 domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289504, updated on 17-Aug-2024

    Summary

    Official Symbol
    Sdad1provided by RGD
    Official Full Name
    SDA1 domain containing 1provided by RGD
    Primary source
    RGD:1359112
    See related
    EnsemblRapid:ENSRNOG00000022229 AllianceGenome:RGD:1359112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in ribosomal large subunit biogenesis and ribosomal large subunit export from nucleus. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human SDAD1 (SDA1 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 71.9), Testes (RPKM 61.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Sdad1 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (16025726..16052565)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (15741489..15768271)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (17247381..17274228)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ADP-ribosyltransferase 3 Neighboring gene C-X-C motif chemokine ligand 10 Neighboring gene C-X-C motif chemokine ligand 9 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene N-acylethanolamine acid amidase Neighboring gene uncharacterized LOC120096576 Neighboring gene protein phosphatase with EF-hand domain 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC94390

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to leukemia inhibitory factor ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein SDA1 homolog
    Names
    SDA1 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006958.2NP_001006959.1  protein SDA1 homolog

      See identical proteins and their annotated locations for NP_001006959.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/Swiss-Prot
      Q5XIQ5
      UniProtKB/TrEMBL
      A0A8I6A4P0, A0A8L2QIL2
      Related
      ENSRNOP00000093210.2, ENSRNOT00000119066.2
      Conserved Domains (2) summary
      pfam05285
      Location:409683
      SDA1; SDA1
      pfam08158
      Location:62111
      NUC130_3NT; NUC130/3NT domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      16025726..16052565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010057348.1 RNA Sequence

      Related
      ENSRNOT00000120318.2