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    S100pbp S100P binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500551, updated on 10-Jul-2024

    Summary

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    Official Symbol
    S100pbpprovided by RGD
    Official Full Name
    S100P binding proteinprovided by RGD
    Primary source
    RGD:1564943
    See related
    EnsemblRapid:ENSRNOG00000007099 AllianceGenome:RGD:1564943
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564943
    Summary
    Predicted to enable calcium-dependent protein binding activity. Predicted to be located in nuclear speck. Predicted to be active in cytosol and nucleus. Orthologous to human S100PBP (S100P binding protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 112.9), Brain (RPKM 100.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See S100pbp in Genome Data Viewer
    Location:
    5q36
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (146778706..146820223, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (141494352..141535752, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (147333890..147375151, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 54 Neighboring gene hippocalcin Neighboring gene fibronectin type III domain containing 5 Neighboring gene U6 spliceosomal RNA Neighboring gene tyrosyl-tRNA synthetase 1 Neighboring gene NHS like 3 Neighboring gene large ribosomal subunit protein uL23-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer. Dowen SE, et al. Am J Pathol, 2005 Jan. PMID 15632002, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    S100P-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134628.1 → NP_001128100.1  S100P-binding protein

      See identical proteins and their annotated locations for NP_001128100.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473968
      UniProtKB/TrEMBL
      A0A8I5ZRF8, A6ISH8, D3ZSX9
      Related
      ENSRNOP00000009436.3, ENSRNOT00000009436.6
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 382
      S100PBPR; S100P-binding protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      146778706..146820223 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288263.1 → XP_063144333.1  S100P-binding protein isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRF8

    2. XM_039110609.2 → XP_038966537.1  S100P-binding protein isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRF8
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 263
      S100PBPR; S100P-binding protein

    3. XM_006238959.4 → XP_006239021.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006239021.1

      UniProtKB/TrEMBL
      A0A8I5ZRF8, A6ISH8, D3ZSX9
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 382
      S100PBPR; S100P-binding protein

    4. XM_006238963.5 → XP_006239025.1  S100P-binding protein isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZRF8
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 305
      S100PBPR; S100P-binding protein

    5. XM_006238961.5 → XP_006239023.1  S100P-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRF8
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 340
      S100PBPR; S100P-binding protein

    6. XM_006238956.5 → XP_006239018.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006239018.1

      UniProtKB/TrEMBL
      A0A8I5ZRF8, A6ISH8, D3ZSX9
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 382
      S100PBPR; S100P-binding protein

    7. XM_063288264.1 → XP_063144334.1  S100P-binding protein isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRF8
      Related
      ENSRNOP00000080960.1, ENSRNOT00000094547.2

    8. XM_063288258.1 → XP_063144328.1  S100P-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRF8

    9. XM_063288260.1 → XP_063144330.1  S100P-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRF8

    10. XM_006238958.5 → XP_006239020.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006239020.1

      UniProtKB/TrEMBL
      A0A8I5ZRF8, A6ISH8, D3ZSX9
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 382
      S100PBPR; S100P-binding protein

    11. XM_063288262.1 → XP_063144332.1  S100P-binding protein isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRF8
      Related
      ENSRNOP00000106058.1, ENSRNOT00000145202.1

    12. XM_063288259.1 → XP_063144329.1  S100P-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZRF8

    13. XM_006238957.5 → XP_006239019.1  S100P-binding protein isoform X1

      See identical proteins and their annotated locations for XP_006239019.1

      UniProtKB/TrEMBL
      A0A8I5ZRF8, A6ISH8, D3ZSX9
      Conserved Domains (1) summary
      pfam15427
      Location:21 → 382
      S100PBPR; S100P-binding protein

    14. XM_063288261.1 → XP_063144331.1  S100P-binding protein isoform X3

    15. XM_008764164.4 → XP_008762386.1  S100P-binding protein isoform X3

      See identical proteins and their annotated locations for XP_008762386.1

      Conserved Domains (1) summary
      pfam15427
      Location:21 → 322
      S100PBPR; S100P-binding protein
    Nucleotide Protein Strain
    Heading Accession and Version

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