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    MRH1 Mrh1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851597, updated on 2-Nov-2024

    Summary

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    Official Symbol
    MRH1
    Official Full Name
    Mrh1p
    Primary source
    SGD:S000002440
    Locus tag
    YDR033W
    See related
    AllianceGenome:SGD:S000002440; FungiDB:YDR033W; VEuPathDB:YDR033W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See MRH1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (508147..509109)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene flavodoxin-like fold family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lys14p Neighboring gene gag-pol fusion protein Neighboring gene gag protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae. Wu K, et al. Biochim Biophys Acta, 2000 Feb 15. PMID 10675524
    2. Functional and transcriptional profiling of non-coding RNAs in yeast reveal context-dependent phenotypes and in trans effects on the protein regulatory network. Balarezo-Cisneros LN, et al. PLoS Genet, 2021 Jan. PMID 33493158, Free PMC Article
    3. Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae. Takabatake A, et al. Appl Microbiol Biotechnol, 2015 Mar. PMID 25503505
    4. Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions. Thayer NH, et al. Proc Natl Acad Sci U S A, 2014 Sep 30. PMID 25228775, Free PMC Article
    5. Functional analysis of six ORFs from Saccharomyces cerevisiae chromosome IV: two-spored asci produced by disruptant of YDR027c and strain-dependent DNA heterogeneity around YDR036c. Aittamaa M, et al. Yeast, 2001 Jul. PMID 11447599

    See all (63) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Yro2 and Mrh1 are involved in tolerance to acetic acid stress.
      Title: Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cellular bud IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mrh1p
    NP_010316.1
    • Protein that localizes primarily to the plasma membrane; also found at the nuclear envelope; long-lived protein that is asymmetrically retained in the plasma membrane of mother cells; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; null mutation confers sensitivity to acetic acid

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      508147..509109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180341.1 → NP_010316.1  TPA: Mrh1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010316.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS17, Q12117
      UniProtKB/TrEMBL
      A6ZXZ5, B3LGN3, B5VFT6, C7GLW6, C8Z4V3, G2WAD8, N1P6F2
      Conserved Domains (1) summary
      COG5524
      Location:4 → 290
      COG5524; Bacteriorhodopsin [Energy production and conversion, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12117.1

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