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    MRPL23 mitochondrial 54S ribosomal protein YmL23 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854321, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MRPL23
    Official Full Name
    mitochondrial 54S ribosomal protein YmL23
    Primary source
    SGD:S000005676
    Locus tag
    YOR150W
    See related
    AllianceGenome:SGD:S000005676; FungiDB:YOR150W; VEuPathDB:YOR150W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL13m
    Summary
    A structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Colocalizes with fungal-type vacuole. Orthologous to human MRPL13 (mitochondrial ribosomal protein L13). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRPL23 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (611999..612490)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Spp2p Neighboring gene glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase Neighboring gene DNA-directed RNA polymerase II core subunit RPB2 Neighboring gene Atg40p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of the MRP-L23 gene encoding the mitochondrial ribosomal protein L23 is lethal for Kluyveromyces lactis but not for Saccharomyces cerevisiae. Murray GL, et al. Curr Genet, 2000 Feb. PMID 10743564
    2. Membrane rafts are involved in intracellular miconazole accumulation in yeast cells. François IE, et al. J Biol Chem, 2009 Nov 20. PMID 19783660, Free PMC Article
    3. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    4. A novel single-cell screening platform reveals proteome plasticity during yeast stress responses. Breker M, et al. J Cell Biol, 2013 Mar 18. PMID 23509072, Free PMC Article
    5. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL23
    NP_014793.1
    • Mitochondrial ribosomal protein of the large subunit; localizes to vacuole in response to H2O2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      611999..612490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183569.1 → NP_014793.1  TPA: mitochondrial 54S ribosomal protein YmL23 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014793.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2K7, Q12487
      UniProtKB/TrEMBL
      A6ZNZ4, B3LJI4, B5VS36, C7GN74, C8ZGQ8, G2WN22, N1NVT3
      Conserved Domains (1) summary
      TIGR01066
      Location:4 → 147
      rplM_bact; ribosomal protein L13, bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12487.1

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