U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RPL27A ribosomal 60S subunit protein L27A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856401, updated on 7-Jul-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    RPL27A
    Gene description
    ribosomal 60S subunit protein L27A
    Primary source
    FungiDB:YHR010W
    Locus tag
    YHR010W
    See related
    SGD:S000001052; AllianceGenome:SGD:S000001052; VEuPathDB:YHR010W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL27
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RPL27A in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    2
    Sequence:
    Chromosome: VIII; NC_001140.6 (126521..127492)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene superoxide dismutase SOD2 Neighboring gene Tda3p Neighboring gene putative serine--tRNA ligase DIA4 Neighboring gene retromer subunit VPS29

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae. Ramos-Sáenz A, et al. RNA, 2019 Nov. PMID 31413149, Free PMC Article
    2. Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Launhardt H, et al. Yeast, 1998 Jul. PMID 9717239
    3. Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. Pöll G, et al. PLoS One, 2017. PMID 28686620, Free PMC Article
    4. Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast. Busti S, et al. Sci Rep, 2016 Jun 16. PMID 27305947, Free PMC Article
    5. Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. Van Dyke MW, et al. J Biol Chem, 2004 Jun 4. PMID 15044472

    See all (97) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ribosomal 60S subunit protein L27A
    NP_011874.1
    • Ribosomal 60S subunit protein L27A; homologous to mammalian ribosomal protein L27, no bacterial homolog; RPL27A has a paralog, RPL27B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      126521..127492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179140.1 → NP_011874.1  TPA: ribosomal 60S subunit protein L27A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011874.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKV5, P0C2H6, P38706
      UniProtKB/TrEMBL
      A6ZSR4, B3LFJ4, C7GMQ1, C8Z630, G2WF78, N1PAK8
      Conserved Domains (1) summary
      cl00354
      Location:1 → 136
      KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C2H6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous