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    PMD1 Pmd1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856869, updated on 17-May-2024

    Summary

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    Gene symbol
    PMD1
    Gene description
    Pmd1p
    Primary source
    FungiDB:YER132C
    Locus tag
    YER132C
    See related
    SGD:S000000934; AllianceGenome:SGD:S000000934; VEuPathDB:YER132C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore formation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PMD1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (425188..430449, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene ribosomal 40S subunit protein S26B Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene type 1 serine/threonine-protein phosphatase catalytic subunit GLC7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Davis DA, et al. Genetics, 2002 Dec. PMID 12524333, Free PMC Article
    2. Identification of a new class of negative regulators affecting sporulation-specific gene expression in yeast. Benni ML, et al. Genetics, 1997 Nov. PMID 9383076, Free PMC Article
    3. Mds3 regulates morphogenesis in Candida albicans through the TOR pathway. Zacchi LF, et al. Mol Cell Biol, 2010 Jul. PMID 20457806, Free PMC Article
    4. The Ras/cAMP pathway and the CDK-like kinase Ime2 regulate the MAPK Smk1 and spore morphogenesis in Saccharomyces cerevisiae. McDonald CM, et al. Genetics, 2009 Feb. PMID 19087957, Free PMC Article
    5. Hitchhiking and epistasis give rise to cohort dynamics in adapting populations. Buskirk SW, et al. Proc Natl Acad Sci U S A, 2017 Aug 1. PMID 28720700, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell redox homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Pmd1p
    NP_011058.3
    • Protein with an N-terminal kelch-like domain; putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions; PMD1 has a paralog, MDS3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      425188..430449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179022.3 → NP_011058.3  TPA: Pmd1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011058.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM38, P32634
      UniProtKB/TrEMBL
      A0A8H8ULZ6, A6ZR86
      Conserved Domains (2) summary
      sd00038
      Location:132 → 184
      Kelch; KELCH repeat [structural motif]
      pfam13964
      Location:132 → 188
      Kelch_6; Kelch motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32634.1

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