U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UTP25 rRNA-binding ribosome biosynthesis protein UTP25 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854717, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UTP25
    Official Full Name
    rRNA-binding ribosome biosynthesis protein UTP25
    Primary source
    SGD:S000001353
    Locus tag
    YIL091C
    See related
    AllianceGenome:SGD:S000001353; FungiDB:YIL091C; VEuPathDB:YIL091C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables U3 snoRNA binding activity and rRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Part of small-subunit processome. Orthologous to human UTP25 (UTP25 small subunit processome component). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UTP25 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (191030..193195, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene mitochondrial 37S ribosomal protein RSM25 Neighboring gene uncharacterized protein Neighboring gene Ice2p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA. Goldfeder MB, et al. FEBS J, 2010 Jul. PMID 20528918
    2. The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit in Saccharomyces cerevisiae. Choque E, et al. RNA Biol, 2011 Nov-Dec. PMID 21941128, Free PMC Article
    3. The DEAD-box RNA helicase-like Utp25 is an SSU processome component. Charette JM, et al. RNA, 2010 Nov. PMID 20884785, Free PMC Article
    4. Systematic Analysis of Phosphatidylinositol-5-phosphate-Interacting Proteins Using Yeast Proteome Microarrays. Herianto S, et al. Anal Chem, 2021 Jan 19. PMID 33302626
    5. The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP. Sardana R, et al. RNA, 2013 Jun. PMID 23604635, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that Nop19p (renamed from YGR251W) interacts preferentially with the DEAH-box RNA helicase Dhr2p and Utp25p.
      Title: The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit in Saccharomyces cerevisiae.
    2. YIL091C/UTP25 is a novel SSU processome component that, along with Utp3, forms the first identified interactions among the different SSU processome subcomplexes
      Title: The DEAD-box RNA helicase-like Utp25 is an SSU processome component.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables U3 snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables U3 snoRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables U3 snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of small-subunit processome IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    rRNA-binding ribosome biosynthesis protein UTP25
    NP_012175.1
    • Nucleolar protein; required for 35S pre-RNA processing and 40S ribosomal subunit biogenesis

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      191030..193195 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179439.1 → NP_012175.1  TPA: rRNA-binding ribosome biosynthesis protein UTP25 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012175.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVJ6, P40498
      UniProtKB/TrEMBL
      G2WG61, N1P0X9
      Conserved Domains (1) summary
      pfam06862
      Location:248 → 720
      UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40498.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous