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    SKA1 Ska1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853845, updated on 17-May-2024

    Summary

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    Gene symbol
    SKA1
    Gene description
    Ska1p
    Primary source
    FungiDB:YKL023W
    Locus tag
    YKL023W
    See related
    SGD:S000001506; AllianceGenome:SGD:S000001506; VEuPathDB:YKL023W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SKA1 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (393721..394554)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene bifunctional uridylate/adenylate kinase Neighboring gene Min9p Neighboring gene anaphase promoting complex subunit CDC16 Neighboring gene Mak11p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions. Ulitsky I, et al. Mol Syst Biol, 2008. PMID 18628749, Free PMC Article
    2. A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes. Zhang E, et al. EMBO J, 2019 Jul 15. PMID 31304628, Free PMC Article
    3. Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels. Eisenberg-Bord M, et al. J Cell Biol, 2021 Nov 1. PMID 34694322, Free PMC Article
    4. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Gupta R, et al. Mol Syst Biol, 2007. PMID 17551511, Free PMC Article
    5. Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length. Lin KW, et al. Nat Commun, 2015 Sep 14. PMID 26365526, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ska1p
    NP_012902.4
    • SKI complex-associated protein; involved in 3'-5' degradation of long 3'UTR-containing mRNA, poorly translated mRNA, and other RNA regions devoid of ribosomes; proposed to assist the cytoplasmic exosome in a Ska1-SKI complex when a direct interaction between the ribosome and the SKI complex is absent

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      393721..394554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179589.4 → NP_012902.4  TPA: Ska1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012902.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXR2, P36103
      UniProtKB/TrEMBL
      A0A6A5PUC2, A6ZZU1, C7GRI2, G2WI07, N1P2G8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36103.2

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