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    VN1R2 vomeronasal 1 receptor 2 [ Homo sapiens (human) ]

    Gene ID: 317701, updated on 17-Jun-2024

    Summary

    Official Symbol
    VN1R2provided by HGNC
    Official Full Name
    vomeronasal 1 receptor 2provided by HGNC
    Primary source
    HGNC:HGNC:19872
    See related
    Ensembl:ENSG00000196131 AllianceGenome:HGNC:19872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    V1RL2
    Summary
    Predicted to enable pheromone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See VN1R2 in Genome Data Viewer
    Location:
    19q13.42
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (53258292..53259602)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (56337798..56339108)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53761545..53762855)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase core subunit V2 pseudogene 1 Neighboring gene zinc finger protein 677 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:53772628-53773290 Neighboring gene vomeronasal 1 receptor 4 Neighboring gene family with sequence similarity 90 member A27, pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables pheromone receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to pheromone IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    vomeronasal type-1 receptor 2
    Names
    G-protein coupled receptor GPCR25
    V1R-like 2
    V1r-like receptor 2
    hGPCR25
    pheromone receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173856.2NP_776255.2  vomeronasal type-1 receptor 2

      See identical proteins and their annotated locations for NP_776255.2

      Status: VALIDATED

      Source sequence(s)
      AC092070, BC130356
      Consensus CDS
      CCDS12862.1
      UniProtKB/Swiss-Prot
      A1L411, Q8NFZ6, Q8TDU4
      Related
      ENSP00000351244.2, ENST00000341702.3
      Conserved Domains (1) summary
      pfam03402
      Location:118369
      V1R; Vomeronasal organ pheromone receptor family, V1R

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      53258292..53259602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      56337798..56339108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)