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    MRP49 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853687, updated on 22-Aug-2024

    Summary

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    Official Symbol
    MRP49
    Primary source
    SGD:S000001650
    Locus tag
    YKL167C
    See related
    AllianceGenome:SGD:S000001650; FungiDB:YKL167C; VEuPathDB:YKL167C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    mL61
    Summary
    A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (133721..134134, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL38/YmL34 Neighboring gene putative serine/threonine protein kinase KKQ8 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK3 Neighboring gene mannose-ethanolamine phosphotransferase MCD4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and function of MRP20 and MRP49, the nuclear genes for two proteins of the 54 S subunit of the yeast mitochondrial ribosome. Fearon K, et al. J Biol Chem, 1992 Mar 15. PMID 1544898
    2. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. Kaur J, et al. EMBO Rep, 2011 Sep 1. PMID 21779004, Free PMC Article
    3. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article
    4. Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. Frazier AE, et al. J Cell Biol, 2006 Feb 13. PMID 16476776, Free PMC Article
    5. The structure of the yeast mitochondrial ribosome. Desai N, et al. Science, 2017 Feb 3. PMID 28154081, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein MRP49
    NP_012754.1
    • Mitochondrial ribosomal protein of the large subunit; not essential for mitochondrial translation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      133721..134134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179733.1 → NP_012754.1  TPA: mitochondrial 54S ribosomal protein MRP49 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012754.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX32, P32388
      UniProtKB/TrEMBL
      A6ZZF7, B3LQT7, C7GJ40, C8ZC06, G2WHM4, N1P0N8
      Conserved Domains (1) summary
      smart00916
      Location:43 → 119
      L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32388.1

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