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    IL13RA2 interleukin 13 receptor subunit alpha 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 403622, updated on 5-Mar-2024

    Summary

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    Official Symbol
    IL13RA2provided by VGNC
    Official Full Name
    interleukin 13 receptor subunit alpha 2provided by VGNC
    Primary source
    VGNC:VGNC:41938
    See related
    Ensembl:ENSCAFG00845016176
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See IL13RA2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (89462267..89540412, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (73868563..73897928, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (88414159..88443524, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (86906747..86936111, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (88581088..88610454, complement)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 2C Neighboring gene COUP transcription factor 2-like Neighboring gene microRNA mir-448 Neighboring gene U6 spliceosomal RNA Neighboring gene transcription factor BTF3-like Neighboring gene small nucleolar RNA SNORA35 Neighboring gene leucine rich repeats and calponin homology domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of canine IL-13 receptor alpha chain (alpha1 and alpha2) cDNAs and detection of corresponding mRNAs in canine tissues. Tang L. Vet Immunol Immunopathol, 2001 May 30. PMID 11389954
    2. Immunopathogenic pathways in canine inflammatory myopathies resemble human myositis. Shelton GD, et al. Vet Immunol Immunopathol, 2006 Sep 15. PMID 16797723

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-13 receptor subunit alpha-2
    Names
    IL-13 receptor subunit alpha-2
    IL-13R subunit alpha-2
    IL-13R-alpha-2
    IL-13RA2
    interleukin 13 receptor alpha chain 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003075.2 → NP_001003075.1  interleukin-13 receptor subunit alpha-2 precursor

      See identical proteins and their annotated locations for NP_001003075.1

      Status: VALIDATED

      Source sequence(s)
      AF314533, CX990270, DN269329, DN341626
      UniProtKB/Swiss-Prot
      Q3HTU7, Q95LF0
      UniProtKB/TrEMBL
      A0A8C0JW16, A0A8C0STV3, A0A8I3P275
      Related
      ENSCAFP00845022834.1, ENSCAFT00845029028.1
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      89462267..89540412 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038448795.1 → XP_038304723.1  interleukin-13 receptor subunit alpha-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3NZM4, A0A8P0TMQ2
      Conserved Domains (2) summary
      cd00063
      Location:237 → 326
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    2. XM_038448801.1 → XP_038304729.1  interleukin-13 receptor subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    3. XM_038448800.1 → XP_038304728.1  interleukin-13 receptor subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    4. XM_038448796.1 → XP_038304724.1  interleukin-13 receptor subunit alpha-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0STV3, A0A8I3P275
      Conserved Domains (2) summary
      cd00063
      Location:257 → 347
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:161 → 254
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    5. XM_038448798.1 → XP_038304726.1  interleukin-13 receptor subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    6. XM_038448799.1 → XP_038304727.1  interleukin-13 receptor subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
      Related
      ENSCAFP00845022643.1, ENSCAFT00845028771.1
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    7. XM_038448797.1 → XP_038304725.1  interleukin-13 receptor subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    8. XM_038448803.1 → XP_038304731.1  interleukin-13 receptor subunit alpha-2 isoform X5

      UniProtKB/Swiss-Prot
      Q3HTU7, Q95LF0
      UniProtKB/TrEMBL
      A0A8C0JW16, A0A8C0STV3, A0A8I3P275
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    9. XM_038448804.1 → XP_038304732.1  interleukin-13 receptor subunit alpha-2 isoform X6

      UniProtKB/TrEMBL
      A0A8I3NZM4, A0A8P0TMQ2
      Conserved Domains (1) summary
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    10. XM_038448802.1 → XP_038304730.1  interleukin-13 receptor subunit alpha-2 isoform X4

      UniProtKB/TrEMBL
      A0A8I3NZM4, A0A8P0TMQ2
      Conserved Domains (2) summary
      cd00063
      Location:237 → 327
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09240
      Location:141 → 234
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      86906747..86936111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      88581088..88610454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      88414159..88443524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      73868563..73897928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95LF0.1 GenPept UniProtKB/Swiss-Prot:Q95LF0

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